Evaluation of bone mineral density and bone turnover markers in patients with non-cirrhotic chronic hepatitis B.
Objective: To evaluate the bone mineral density (BMD) and the biochemical markers of bone turnover in non-cirrhotic chronic hepatitis B patients. Material and Methods: We compared 18-65 years old non-cirrhotic chronic hepatitis B patients and healthy controls for BMD and biochemical markers of bone...
| Published in: | Turkiye Klinikleri Journal of Medical Sciences Vol. 32; no. 2; pp. 324 - 331 |
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| Main Authors: | , , , , , , |
| Format: | research tables/charts Journal Article |
| Published: |
Turkiye Klinikleri
Apr2012
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104545982&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104545982 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 13000292 1VOP jtl: Turkiye Klinikleri Journal of Medical Sciences issn: 13000292 maglogo: N pubinfo: dt: Apr2012 vid: 32 iid: 2 pid: 67298 pub: Turkiye Klinikleri artinfo: ui: 104545982 2011506054 10.5336/medsci.2011-22718 104545982 ppf: 324 ppct: 7 formats: fmt: @attributes: type: P tig: atl: Evaluation of bone mineral density and bone turnover markers in patients with non-cirrhotic chronic hepatitis B. aug: au: Celebi, Guven Sarikaya, Selda Ozdolap, Senay Mungan, Gorkem Ankarali, Handan Celik, Yavuz Akduman, Deniz affil: Infectious Diseases and Clinical Microbiology sug: subj: Biological Markers Bone Density Evaluation Hepatitis B, Chronic Adolescence Adult Aged Chi Square Test Comparative Studies Human Mann-Whitney U Test Middle Age Pearson's Correlation Coefficient Prospective Studies T-Tests Adolescent: 13-18 years Adult: 19-44 years Aged: 65+ years Middle Aged: 45-64 years ab: Objective: To evaluate the bone mineral density (BMD) and the biochemical markers of bone turnover in non-cirrhotic chronic hepatitis B patients. Material and Methods: We compared 18-65 years old non-cirrhotic chronic hepatitis B patients and healthy controls for BMD and biochemical markers of bone turnover. BMD was measured at the lumbar spine and the left hip using DXA. Results: There were 31 hepatitis B patients (19 males, 12 females) and 72 healthy controls (56 males, 16 females) in the study. Their mean age was 37.4 ± 10.0 years in the study group and 38.5 ± 7.1 years in the controls. There were no differences between the two groups for the mean BMD levels and T scores. However, left hip BMD and T scores were significantly lower in male patients with chronic hepatitis B infection when compared to males in the control group. Serum calcium, phosphate, osteocalcine, intact parathyroid hormone, deoxypyridinoline and 25-hydroxycholecalciferol levels did not differ between the groups. Conclusion: In our study, left hip BMD and T scores were found to be significantly lower in the male patients with chronic hepatitis B infection when compared to males in the control group, however a significant difference was not detected when all cases were compared with the control group. Therefore, we suppose that further studies on a larger population are needed in this issue. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: Turkish refInfo: holdings: @attributes: islocal: N |
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