There is no relationship between the number of subsequent pregnancy losses and thrombophilic factors.
Objective: If there are two previous miscarriages, the risk of miscarriage in the next pregnancy is 26% . Presence of three previous miscarriages increases this risk upto 32%. We have aimed to find whether or not there is a difference between the women with habitual abortion (three or more fetal los...
| Publicado en: | Turkiye Klinikleri Journal of Medical Sciences Vol. 32; no. 2; pp. 376 - 382 |
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| Autores principales: | , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Turkiye Klinikleri
Apr2012
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104545987&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104545987 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 13000292 1VOP jtl: Turkiye Klinikleri Journal of Medical Sciences issn: 13000292 maglogo: N pubinfo: dt: Apr2012 vid: 32 iid: 2 pid: 67298 pub: Turkiye Klinikleri artinfo: ui: 104545987 2011506096 10.5336/medsci.2011-23624 104545987 ppf: 376 ppct: 6 formats: fmt: @attributes: type: P tig: atl: There is no relationship between the number of subsequent pregnancy losses and thrombophilic factors. aug: au: Karadeniz, R. Sinan Altay, M. Metin Ensari, Tugba Altun Erol, A. Okyar Ozdogan, Serdinc Haberal, Ali affil: Clinic of Gynecology and Obstetrics, Etlik Zübeyde Han?m Maternity and Women's Health Teaching and Research Hospital, Ankara sug: subj: Abortion, Habitual Hematologic Diseases Classification Female Human Pregnancy Female ab: Objective: If there are two previous miscarriages, the risk of miscarriage in the next pregnancy is 26% . Presence of three previous miscarriages increases this risk upto 32%. We have aimed to find whether or not there is a difference between the women with habitual abortion (three or more fetal losses) and women with two fetal losses in relation to thrombophilic factors. Material and Methods: A total of 108 women aged between 17-40 years who admitted to the infertility department were included in the study. None of the patients were pregnant. Patients were divided into two groups as women with three or more subsequent pregnancy losses, which was defined as habitual abortus, and women with two abortuses, and then both groups underwent thrombophilia workup. There were 66 patients in the first group and 42 patients in the second group. Results: We did not find any significant difference between the groups in relation to folic acid, vitamin B12, homocystein, antithrombin III, protein S levels or presence of activated protein C resistance, prothrombin G mutation, and factor V mutation. There were no pathological findings on hysterosalpingography and pelvic ultrasonography of the patients. Conclusion: As a result, we believe that investigation for thrombophilia should be performed in women with two recurrent miscarriages (without regarding the early or late abortions), before the occurence of three fetal losses. One may expect that this approach will protect patients from losing their next pregnancies by preventing late diagnosis and the treatment of thrombophilia. However, our opinion should be supported by prospective cohort studies with a greater sample size. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: Turkish refInfo: holdings: @attributes: islocal: N |
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