Role of real-time endobronchial ultrasound-guided transbronchial needle aspiration in the diagnosis and mediastinal staging of lung cancer.

Objective: Real-time endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a minimally invasive new diagnostic tool used for diagnosis and mediastinal staging of lung cancer. The aim of this study is to evaluate the role of real-time EBUS-TBNA for diagnosis of lymph nodes i...

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Publicado en:Turkiye Klinikleri Journal of Medical Sciences Vol. 32; no. 2; pp. 407 - 415
Autores principales: Alatas, Fosun, Dundar, Emine, Yildirim, Huseyin, Metintas, Muzaffer, Akdogan, Guntulu
Formato: diagnostic images research tables/charts Journal Article
Publicado: Turkiye Klinikleri Apr2012
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Apr2012
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      pub: Turkiye Klinikleri
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        2011506140
        10.5336/medsci.2011-24056
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        atl: Role of real-time endobronchial ultrasound-guided transbronchial needle aspiration in the diagnosis and mediastinal staging of lung cancer.
      aug:
        au:
          Alatas, Fosun
          Dundar, Emine
          Yildirim, Huseyin
          Metintas, Muzaffer
          Akdogan, Guntulu
        affil: Departments of Chest Diseases
      sug:
        subj:
          Biopsy, Needle Methods
          Lung Neoplasms Classification
          Lymph Nodes Physiopathology
          Data Analysis Software
          Human
          McNemar's Test
          Time Factors
          Tomography, X-Ray Computed
          Ultrasonography Methods
      ab: Objective: Real-time endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a minimally invasive new diagnostic tool used for diagnosis and mediastinal staging of lung cancer. The aim of this study is to evaluate the role of real-time EBUS-TBNA for diagnosis of lymph nodes in patients with suspected lung cancer who had mediastinal and/or hilar lymph nodes. Material and Methods: Between April 2009 and January 2011, 52 patients with mediastinal and/or hilar lymphadenopathy suspected for lung cancer referred for TBNA were enrolled in the study. Results: Of 97 lymph node biopsy specimens, 94 were eligible for diagnosis. Of three patients with malignancy negative lymph node biopsy specimens, two gave their consents and underwent mediastinoscopy. The result of one patient was negative, and the other one was positive for malignancy. The third patient was accepted to have a non malignant disease since the positron emission tomography of lymph node was negative for malignancy and remained stable and non-malignant during the follow-up. The sensitivity and specificity of EBUS-TBNA in the diagnostic evaluation of mediastinal and/or hilar lymph nodes of patients with suspected for lung cancer were 98.9% and 100%, respectively. Twelve N3 lymph nodes were diagnosed as positive for malignancy. Twenty three patients without endobronchial lesions on conventional bronchoscopy were diagnosed as lung cancer by real-time EBUS-TBNA. No complications were recorded during the procedures. Conclusion: Real-time EBUS-TBNA is an effective and reliable diagnostic procedure. Moreover, it is a very useful tool for diagnosis of lesions which cannot be reached with the conventional bronchoscope.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: Turkish
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