Effect of Blood Donation Mediated Volume Reduction on Right Ventricular Function Parameters in Healthy Subjects.

Purpose: We aimed to investigate the effect of controlled and limited volume change by the blood donation model to the right ventricular (RV) function via different echocardiographic parameters in healthy adults. Methods: Study population was composed of 71 healthy subjects who were volunteers for b...

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Publicado en:Echocardiography Vol. 29; no. 4; pp. 451 - 455
Autores principales: Kucukdurmaz, Zekeriya, Karapinar, Hekim, Karavelioğlu, Yusuf, Açar, Göksel, Gul, Ibrahim, Emiroglu, Mehmet Yunus, Bulut, Mustafa, Esen, Ali Metin
Formato: research tables/charts Journal Article
Publicado: Wiley-Blackwell Apr2012
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Apr2012
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      pub: Wiley-Blackwell
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        atl: Effect of Blood Donation Mediated Volume Reduction on Right Ventricular Function Parameters in Healthy Subjects.
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        au:
          Kucukdurmaz, Zekeriya
          Karapinar, Hekim
          Karavelioğlu, Yusuf
          Açar, Göksel
          Gul, Ibrahim
          Emiroglu, Mehmet Yunus
          Bulut, Mustafa
          Esen, Ali Metin
        affil: Department of Cardiology, Cumhuriyet University, Medical School, Sivas, Turkey
      sug:
        subj:
          Blood Donors
          Blood Volume Evaluation
          Diagnostic Imaging Methods
          Heart Ventricle, Right Ultrasonography
          Blood Donation
          Echocardiography, Doppler
          Echocardiography, Doppler, Pulsed
          Human
          Male
          Female
          Adult
          Middle Age
          Pretest-Posttest Design
          Outcome Assessment
          Intrarater Reliability
          Descriptive Statistics
          Data Analysis Software
          Paired T-Tests
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Male
          Female
      ab: Purpose: We aimed to investigate the effect of controlled and limited volume change by the blood donation model to the right ventricular (RV) function via different echocardiographic parameters in healthy adults. Methods: Study population was composed of 71 healthy subjects who were volunteers for blood donation and evaluated before and after 450 mL blood donation. Pulsed-wave Doppler of the RV inflow and tissue Doppler of tricuspid lateral annulus, and tricuspid annular plane systolic excursion (TAPSE) were assessed. Results: E velocity of inflow decreased significantly (67.6 ± 15.9 vs 60.9 ± 12.2, P = 0.006). S' and A' velocities did not change (15.3 ± 3.2 vs 15.2 ± 2.5 cm/s, P = NS; 14.1 ± 3.3 vs 13.4 ± 3.1 cm/s, P = NS, respectively) but E' showed significant decrease (13.7 ± 2.9 vs 12.2 ± 3.2 cm/s, P = 0.011). E'/A' ratio and E/E' ratio were found to be unchanged (1.0 ± 0.3 vs 1.0 ± 0.4, P = NS; 5.1 ± 2 vs 5.3 ± 2, P = NS, respectively). Myocardial performance index (MPI) was found to be increased but ejection time obtained from the tricuspid annulus did not change (0.50 ± 0.13 vs 0.54 ± 0.11, P = 0.040; 243 ± 37 vs 240 ± 27, P = NS, respectively). Isovolumetric relaxation and contraction times showed difference close to the significance limit (56 ± 19 vs 64 ± 23 ms, P = 0.055; 61 ± 16 vs 67 ± 16 ms, P = 0.062, respectively). TAPSE decreased significantly (2.62 ± 0.29 vs 2.41 ± 0.27 mm, P = 0.005). Conclusion: E' velocity and TAPSE were sensitive to a volume reduction as little as 450 mL in healthy subjects. MPI index of the tricuspid annulus is less sensitive than E' and TAPSE but need much care under changing volume state. However S' and A' velocity and E'/A' ratio were found to be resistant to the effects of volume depletion. (Echocardiography 2012;29:451-454)
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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