Validation of classification algorithms for childhood diabetes identified from administrative data.

Vanderloo SE, Johnson JA, Reimer K, McCrea P, Nuernberger K, Krueger H, Aydede SK, Collet J-P, Amed S. Validation of classification algorithms for childhood diabetes identified from administrative data. Objective: Type 1 diabetes is the most common form of diabetes among children; however, the propo...

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Publicado en:Pediatric Diabetes Vol. 13; no. 3; pp. 229 - 235
Autores principales: Vanderloo, Saskia E, Johnson, Jeffrey A, Reimer, Kim, McCrea, Patrick, Nuernberger, Kimberly, Krueger, Hans, Aydede, Sema K, Collet, Jean-Paul, Amed, Shazhan
Formato: algorithm research Journal Article
Publicado: Wiley-Blackwell May2012
Acceso en línea:Ver este registro en EBSCOhost
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      dt: May2012
      vid: 13
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        10.1111/j.1399-5448.2011.00795.x
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        atl: Validation of classification algorithms for childhood diabetes identified from administrative data.
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        au:
          Vanderloo, Saskia E
          Johnson, Jeffrey A
          Reimer, Kim
          McCrea, Patrick
          Nuernberger, Kimberly
          Krueger, Hans
          Aydede, Sema K
          Collet, Jean-Paul
          Amed, Shazhan
        affil: School of Public Health, University of Alberta, Edmonton, AB, Canada
      sug:
        subj:
          Diabetes Mellitus, Type 1 Diagnosis
          Classification Algorithms
          Pediatrics
          Diabetes Mellitus Physiopathology
          Diabetes Mellitus, Type 2 Diagnosis
          Professional Organizations
          Descriptive Statistics
          Demography
          Male
          Female
          Canada
          Hypoglycemia
          Hospitalization Evaluation
          Patient Discharge
          Insulin Administration and Dosage
          Metformin Administration and Dosage
          Human
          Child
          Child: 6-12 years
          Male
          Female
      ab: Vanderloo SE, Johnson JA, Reimer K, McCrea P, Nuernberger K, Krueger H, Aydede SK, Collet J-P, Amed S. Validation of classification algorithms for childhood diabetes identified from administrative data. Objective: Type 1 diabetes is the most common form of diabetes among children; however, the proportion of cases of childhood type 2 diabetes is increasing. In Canada, the National Diabetes Surveillance System (NDSS) uses administrative health data to describe trends in the epidemiology of diabetes, but does not specify diabetes type. The objective of this study was to validate algorithms to classify diabetes type in children <20 yr identified using the NDSS methodology. Patients and methods: We applied the NDSS case definition to children living in British Columbia between 1 April 1996 and 31 March 2007. Through an iterative process, four potential classification algorithms were developed based on demographic characteristics and drug-utilization patterns. Each algorithm was then validated against a gold standard clinical database. Results: Algorithms based primarily on an age rule (i.e., age <10 at diagnosis categorized type 1 diabetes) were most sensitive in the identification of type 1 diabetes; algorithms with restrictions on drug utilization (i.e., no prescriptions for insulin ± glucose monitoring strips categorized type 2 diabetes) were most sensitive for identifying type 2 diabetes. One algorithm was identified as having the optimal balance of sensitivity (Sn) and specificity (Sp) for the identification of both type 1 (Sn: 98.6%; Sp: 78.2%; PPV: 97.8%) and type 2 diabetes (Sn: 83.2%; Sp: 97.5%; PPV: 73.7%). Conclusions: Demographic characteristics in combination with drug-utilization patterns can be used to differentiate diabetes type among cases of pediatric diabetes identified within administrative health databases. Validation of similar algorithms in other regions is warranted.
      pubtype: Academic Journal
      doctype:
        algorithm
        research
        Journal Article
      ougenre: Article
    language: English
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