Computer-aided detection system performance on current and previous digital mammograms in patients with contralateral metachronous breast cancer.

Background: The computer-aided detection (CAD) system is widely used for screening mammography. The performance of the CAD system for contralateral breast cancer has not been reported for women with a history of breast cancer. Purpose: To retrospectively evaluate the performance of a CAD system on c...

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Published in:Acta Radiologica Vol. 53; no. 4; pp. 376 - 382
Main Authors: Kim SJ, Moon WK, Cho N, Chang JM, Kim, Seung Ja, Moon, Woo Kyung, Cho, Nariya, Chang, Jung Min
Format: research Journal Article
Published: Sage Publications Inc. May2012
Online Access:View this record in EBSCOhost
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      dt: May2012
      vid: 53
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      pub: Sage Publications Inc.
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        10.1258/ar.2012.110521
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        atl: Computer-aided detection system performance on current and previous digital mammograms in patients with contralateral metachronous breast cancer.
      aug:
        au:
          Kim SJ
          Moon WK
          Cho N
          Chang JM
          Kim, Seung Ja
          Moon, Woo Kyung
          Cho, Nariya
          Chang, Jung Min
        affil: Department of Radiology, Seoul Metropolitan Government - Seoul National University Boramae Medical Center, Korea
      sug:
        subj:
          Breast Neoplasms Radiography
          Mammography
          Neoplasms, Second Primary Radiography
          Radiographic Image Interpretation, Computer-Assisted Methods
          Adult
          Aged
          Aged, 80 and Over
          Breast Neoplasms Surgery
          Diagnosis, Differential
          False Positive Results
          Female
          Prospective Studies
          Human
          Mastectomy Methods
          Middle Age
          Retrospective Design
          Sensitivity and Specificity
          Adult: 19-44 years
          Aged: 65+ years
          Aged, 80 & over
          Middle Aged: 45-64 years
          Female
      ab: Background: The computer-aided detection (CAD) system is widely used for screening mammography. The performance of the CAD system for contralateral breast cancer has not been reported for women with a history of breast cancer. Purpose: To retrospectively evaluate the performance of a CAD system on current and previous mammograms in patients with contralateral metachronous breast cancer. Material and Methods: During a 3-year period, 4945 postoperative patients had follow-up examinations, from whom we selected 55 women with contralateral breast cancers. Among them, 38 had visible malignant signs on the current mammograms. We analyzed the sensitivity and false-positive marks of the system on the current and previous mammograms according to lesion type and breast density. Results: The total visible lesion components on the current mammograms included 27 masses and 14 calcifications in 38 patients. The case-based sensitivity for all lesion types was 63.2% (24/38) with false-positive marks of 0.71 per patient. The lesion-based sensitivity for masses and calcifications was 59.3% (16/27) and 71.4% (10/14), respectively. The lesion-based sensitivity for masses in fatty and dense breasts was 68.8% (11/16) and 45.5% (5/11), respectively. The lesion-based sensitivity for calcifications in fatty and dense breasts was 100.0% (3/3) and 63.6% (7/11), respectively. The total visible lesion components on the previous mammograms included 13 masses and three calcifications in 16 patients, and the sensitivity for all lesion types was 31.3% (5/16) with false-positive marks of 0.81 per patient. On these mammograms, the sensitivity for masses and calcifications was 30.8% (4/13) and 33.3% (1/3), respectively. The sensitivity in fatty and dense breasts was 28.6% (2/7) and 33.3% (3/9), respectively. Conclusion: In the women with a history of breast cancer, the sensitivity of the CAD system in visible contralateral breast cancer was lower than in most previous reports using the same CAD system probably due to the relatively small size, subtlety of the lesion findings, and dense parenchymal pattern.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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