Differential diagnosis of vertebral compression fracture using in-phase/opposed-phase and short TI inversion recovery imaging.

Background: Magnetic resonance imaging (MRI) is highly useful for detecting diseases of the bone marrow. The sensitivity for detecting compression fracture is very high, but specificity is low for differential diagnosis between malignant and benign cases. Purpose: To evaluate the usefulness of in-ph...

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Publicado en:Acta Radiologica Vol. 53; no. 4; pp. 450 - 456
Autores principales: Ogura A, Hayakawa K, Maeda F, Saeki F, Syukutani A, Shibutani S, Kuroda E
Formato: research Journal Article
Publicado: Sage Publications Inc. May2012
Acceso en línea:Ver este registro en EBSCOhost
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      dt: May2012
      vid: 53
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      pub: Sage Publications Inc.
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        atl: Differential diagnosis of vertebral compression fracture using in-phase/opposed-phase and short TI inversion recovery imaging.
      aug:
        au:
          Ogura A
          Hayakawa K
          Maeda F
          Saeki F
          Syukutani A
          Shibutani S
          Kuroda E
        affil: Department of Radiology, Kyoto City Hospital, Kyoto, Japan.
      sug:
        subj:
          Fractures, Compression Diagnosis
          Magnetic Resonance Imaging Methods
          Spinal Fractures Diagnosis
          Spinal Neoplasms Diagnosis
          Adult
          Aged
          Aged, 80 and Over
          Diagnosis, Differential
          Female
          Fractures, Compression Pathology
          Human
          Male
          Middle Age
          Phantoms, Imaging
          Retrospective Design
          Sensitivity and Specificity
          Spinal Fractures Pathology
          Spinal Neoplasms
          Adult: 19-44 years
          Aged: 65+ years
          Aged, 80 & over
          Middle Aged: 45-64 years
          Female
          Male
      ab: Background: Magnetic resonance imaging (MRI) is highly useful for detecting diseases of the bone marrow. The sensitivity for detecting compression fracture is very high, but specificity is low for differential diagnosis between malignant and benign cases. Purpose: To evaluate the usefulness of in-phase/opposed-phase and short TI inversion recovery (STIR) magnetic resonance imaging (MRI) of bone marrow for differentiation between benign and malignant vertebral compression fractures. Material and Methods: A retrospective review of 66 patients with 70 vertebral compression fractures was performed. The signal intensity ratio (SIR) defined as SIR (opposed/in) was calculated from in-phase/ opposed-phase MR images, and the signal intensity ratio as SIR (STIR) was calculated from STIR MR images. The relationships between values of SIR (opposed/in) and SIR (STIR) and the differential diagnosis of malignant vs. benign fractures were considered. Results: When SIR (opposed/in) was less than 1.0, bone marrow was benign. The bone marrow was malignant when both SIR (opposed/in) was greater than 1.0 and SIR (STIR) was less than 2.0. Conclusion: In cases of acute compression fracture, malignant bone marrow showed SIR(STIR) values less than 2.0 and SIR (in/opposed) greater than 1.0. In contrast, benign bone marrow showed SIR (STIR) values greater than 2.5. For chronic compression fracture, malignant bone marrow showed SIR (in/opposed) greater than 1.0. Bone marrow was benign in all cases with SIR (in/opposed) less than 1.0.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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