Consensus Versus Disagreement in Imaging Research: a Case Study Using the LIDC Database.

Traditionally, image studies evaluating the effectiveness of computer-aided diagnosis (CAD) use a single label from a medical expert compared with a single label produced by CAD. The purpose of this research is to present a CAD system based on Belief Decision Tree classification algorithm, capable o...

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Publicado en:Journal of Digital Imaging Vol. 25; no. 3; pp. 423 - 437
Autores principales: Zinovev, Dmitriy, Duo, Yujie, Raicu, Daniela, Furst, Jacob, Armato, Samuel
Formato: diagnostic images research tables/charts Journal Article
Publicado: Springer Nature Jun2012
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jun2012
      vid: 25
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      pub: Springer Nature
      place: New York, New York
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        atl: Consensus Versus Disagreement in Imaging Research: a Case Study Using the LIDC Database.
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          Zinovev, Dmitriy
          Duo, Yujie
          Raicu, Daniela
          Furst, Jacob
          Armato, Samuel
        affil: College of Computing and Digital Media, DePaul University, 243 S. Wabash Ave Chicago 60604 USA
      sug:
        subj:
          Diagnostic Imaging
          Decision Trees
          Diagnosis, Computer Assisted
          Radiographic Image Interpretation, Computer-Assisted
          Tomography, X-Ray Computed
          Thorax
          Algorithms
          Evaluation Research
          ROC Curve
          Human
      ab: Traditionally, image studies evaluating the effectiveness of computer-aided diagnosis (CAD) use a single label from a medical expert compared with a single label produced by CAD. The purpose of this research is to present a CAD system based on Belief Decision Tree classification algorithm, capable of learning from probabilistic input (based on intra-reader variability) and providing probabilistic output. We compared our approach against a traditional decision tree approach with respect to a traditional performance metric (accuracy) and a probabilistic one (area under the distance-threshold curve-AuC). The probabilistic classification technique showed notable performance improvement in comparison with the traditional one with respect to both evaluation metrics. Specifically, when applying cross-validation technique on the training subset of instances, boosts of 28.26% and 30.28% were noted for the probabilistic approach with respect to accuracy and AuC, respectively. Furthermore, on the validation subset of instances, boosts of 20.64% and 23.21% were noted again for the probabilistic approach with respect to the same two metrics. In addition, we compared our CAD system results with diagnostic data available for a small subset of the Lung Image Database Consortium database. We discovered that when our CAD system errs, it generally does so with low confidence. Predictions produced by the system also agree with diagnoses of truly benign nodules more often than radiologists, offering the possibility of reducing the false positives.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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