Comparative effectiveness of mechanically and electrically powered negative pressure wound therapy devices: A multicenter randomized controlled trial.
This study was designed to compare the ultraportable mechanically powered Smart Negative Pressure ( SNaP) Wound Care System ( Spiracur, Sunnyvale, CA) with the electrically powered Vacuum- Assisted Closure ( VAC) Therapy System (Kinetic Concepts, Inc. [ KCI], San Antonio, TX) in a multicenter, compa...
| Publicado en: | Wound Repair & Regeneration Vol. 20; no. 3; pp. 332 - 342 |
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| Autores principales: | , , , |
| Formato: | research tables/charts randomized controlled trial Journal Article |
| Publicado: |
Wiley-Blackwell
May/Jun2012
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104565426&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104565426 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 10671927 DPV jtl: Wound Repair & Regeneration issn: 10671927 maglogo: Y pubinfo: dt: May/Jun2012 vid: 20 iid: 3 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 104565426 74981256 10.1111/j.1524-475X.2012.00780.x NLM22564228 104565426 ppf: 332 ppct: 10 formats: fmt: @attributes: type: P tig: atl: Comparative effectiveness of mechanically and electrically powered negative pressure wound therapy devices: A multicenter randomized controlled trial. aug: au: Armstrong, David G. Marston, William A. Reyzelman, Alexander M. Kirsner, Robert S. affil: wrr780-aff-0001 sug: subj: Negative Pressure Wound Therapy Methods Treatment Outcomes Human Funding Source Randomized Controlled Trials Leg Ulcer Random Assignment Kaplan-Meier Estimator Multicenter Studies Prospective Studies Wilcoxon Rank Sum Test Survival Analysis Data Analysis Software Male Female Middle Age Aged Aged, 80 and Over Descriptive Statistics Middle Aged: 45-64 years Aged: 65+ years Aged, 80 & over Male Female ab: This study was designed to compare the ultraportable mechanically powered Smart Negative Pressure ( SNaP) Wound Care System ( Spiracur, Sunnyvale, CA) with the electrically powered Vacuum- Assisted Closure ( VAC) Therapy System (Kinetic Concepts, Inc. [ KCI], San Antonio, TX) in a multicenter, comparative efficacy, noninferiority-powered, randomized controlled trial. We enrolled 132 people with noninfected, nonischemic, nonplantar lower extremity diabetic and venous wounds. Each subject was randomly assigned (1:1) to treatment with either system in conjunction with appropriate off-loading and compression therapy. The trial evaluated treatment for up to 16 weeks or complete wound closure (defined as complete reepithelialization without drainage). Primary end point analysis of wound size reduction found that SNaP-treated subjects demonstrated noninferiority to the VAC-treated subjects at 4, 8, 12, and 16 weeks ( p = 0.0030, 0.0130, 0.0051, and 0.0044, respectively). Kaplan- Meier analysis showed no significant difference in complete wound closure between SNaP- and VAC-treated subjects at all time points. Device related adverse events and complications such as infection were also similar between treatment groups. These data support similar wound healing outcomes between the SNaP system and the VAC system in the population studied. pubtype: Academic Journal doctype: research tables/charts randomized controlled trial Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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