Fractal dimension values of cerebral and cerebellar activity in rats loaded with aluminium.
Aluminium interferes with a variety of cellular metabolic processes in the mammalian nervous system and its intake might increase a risk of developing Alzheimer's disease (AD). While cerebral involvement even at the early stages of intoxication is well known, the role of cerebellum is underestimated...
| Publicado en: | Medical & Biological Engineering & Computing Vol. 48; no. 7; pp. 671 - 680 |
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| Autores principales: | , , , , , , , , , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Springer Nature
Jul2010
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104569238&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104569238 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 01400118 PO0 jtl: Medical & Biological Engineering & Computing issn: 01400118 maglogo: N pubinfo: dt: Jul2010 vid: 48 iid: 7 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 104569238 NLM20424923 2010687583 10.1007/s11517-010-0620-3 NLM20424923 104569238 ppf: 671 ppct: 9 formats: fmt: @attributes: type: P tig: atl: Fractal dimension values of cerebral and cerebellar activity in rats loaded with aluminium. aug: au: Kekovic G Culic M Martac L Stojadinovic G Capo I Lalosevic D Sekulic S Kekovic, Goran Culic, Milka Martac, Ljiljana Stojadinovic, Gordana Capo, Ivan Lalosevic, Dusan Sekulic, Slobodan affil: Institute for Biological Research "S. Stankovic", University of Belgrade, Bulevar despota Stefana 142, Belgrade, Serbia sug: subj: Aluminum Cerebellum Drug Effects Cerebral Cortex Drug Effects Algorithms Animals Cerebellum Physiopathology Cerebral Cortex Physiopathology Electroencephalography Electroencephalography Methods Mathematics Male Rats Signal Processing, Computer Assisted Male ab: Aluminium interferes with a variety of cellular metabolic processes in the mammalian nervous system and its intake might increase a risk of developing Alzheimer's disease (AD). While cerebral involvement even at the early stages of intoxication is well known, the role of cerebellum is underestimated. Our aim was to investigate cerebral and cerebellar electrocortical activity in adult male rats exposed to chronic aluminium treatment by nonlinear analytic tools. The adult rats in an aluminium-treated group were injected by AlCl(3), intraperitoneally (2 mg Al/kg, daily for 4 weeks). Fractal analysis of brain activity was performed off-line using Higuchi's algorithm. The average fractal dimension of electrocortical activity in aluminium-treated animals was lower than the average fractal dimension of electrocortical activity in the control rats, at cerebral but not at cerebellar level. The changes in the stationary and nonlinear properties of time series were more expressed in cerebral electrocortical activity than in cerebellar activity. This can be useful for developing effective diagnostic and therapeutic strategies in neurodegenerative diseases. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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