Spontaneous contractions of isolated rat portal vein under temperature perturbations.

We studied nonlinear dynamics underlying spontaneous rhythmical contractions of isolated rat portal vein. The signals were acquired at four different temperatures important in isolated blood vessels preparations: 4, 22, 37 and 40 degrees C. To characterize the system's nonlinearity, we calculated th...

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Publicado en:Medical & Biological Engineering & Computing Vol. 48; no. 9; pp. 887 - 895
Autores principales: Vuksanovic V, Gal V, Platisa MM, Gojkovic-Bukarica L, Vuksanović, Vesna, Gal, Vera, Platisa, Mirjana M, Gojković-Bukarica, Ljiljana
Formato: research Journal Article
Publicado: Springer Nature Sep2010
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Springer Nature
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        atl: Spontaneous contractions of isolated rat portal vein under temperature perturbations.
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        au:
          Vuksanovic V
          Gal V
          Platisa MM
          Gojkovic-Bukarica L
          Vuksanović, Vesna
          Gal, Vera
          Platisa, Mirjana M
          Gojković-Bukarica, Ljiljana
        affil: Institute of Biophysics, Faculty of Medicine, University of Belgrade, Belgrade, Serbia
      sug:
        subj:
          Portal Vein Physiology
          Vasoconstriction Physiology
          Animals
          Physics
          Muscle, Smooth Physiology
          Periodicity
          Rats
          Temperature
      ab: We studied nonlinear dynamics underlying spontaneous rhythmical contractions of isolated rat portal vein. The signals were acquired at four different temperatures important in isolated blood vessels preparations: 4, 22, 37 and 40 degrees C. To characterize the system's nonlinearity, we calculated the largest Lyapunov exponent, sample entropy and scaling exponents. Evidence for nonlinearity was provided by analysis of surrogate data generated from the phase-randomized Fourier transform of the original sequences. Positive values of the largest Lyapunov exponent were obtained for the time series recorded under applied conditions, indicating that the system preserves its chaotic deterministic nature even far from the physiological temperature range. Scaling exponents revealed three distinctive regions with different correlation properties. The calculated measures that characterize the time series obtained at 4 degrees C were significantly different from those derived from data obtained at higher temperatures. System's dynamics becomes more complex or less predictable as temperature approaches physiological value. The computation of the largest Lyapunov exponent, sample entropy and correlation measures gave an insight into the complex dynamics of the isolated blood vessels rhythmicity. We identified different modes of rhythmical contractions of isolated rat portal vein which could improve understanding of possible control mechanisms in vivo.
      pubtype: Academic Journal
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        Journal Article
      ougenre: Article
    language: English
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