Automated detection of obstructive sleep apnoea syndrome from oxygen saturation recordings using linear discriminant analysis.

Nocturnal polysomnography (PSG) is the gold-standard to diagnose obstructive sleep apnoea syndrome (OSAS). However, it is complex, expensive, and time-consuming. We present an automatic OSAS detection algorithm based on classification of nocturnal oxygen saturation (SaO(2)) recordings. The algorithm...

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Publicado en:Medical & Biological Engineering & Computing Vol. 48; no. 9; pp. 895 - 903
Autores principales: Marcos JV, Hornero R, Alvarez D, Campo FD, Aboy M, Marcos, J Víctor, Hornero, Roberto, Alvarez, Daniel, Del Campo, Félix, Aboy, Mateo
Formato: research Journal Article
Publicado: Springer Nature Sep2010
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Automated detection of obstructive sleep apnoea syndrome from oxygen saturation recordings using linear discriminant analysis.
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          Marcos JV
          Hornero R
          Alvarez D
          Campo FD
          Aboy M
          Marcos, J Víctor
          Hornero, Roberto
          Alvarez, Daniel
          Del Campo, Félix
          Aboy, Mateo
        affil: ETSI de Telecomunicación, University of Valladolid, Valladolid, Spain
      sug:
        subj:
          Oxygen Blood
          Sleep Apnea, Obstructive Diagnosis
          Adult
          Aged
          Algorithms
          Female
          Human
          Linear Regression
          Male
          Middle Age
          Oximetry Methods
          Prospective Studies
          Signal Processing, Computer Assisted
          Adult: 19-44 years
          Aged: 65+ years
          Middle Aged: 45-64 years
          Female
          Male
      ab: Nocturnal polysomnography (PSG) is the gold-standard to diagnose obstructive sleep apnoea syndrome (OSAS). However, it is complex, expensive, and time-consuming. We present an automatic OSAS detection algorithm based on classification of nocturnal oxygen saturation (SaO(2)) recordings. The algorithm makes use of spectral and nonlinear analysis for feature extraction, principal component analysis (PCA) for preprocessing and linear discriminant analysis (LDA) for classification. We conducted a study to characterize and prospectively validate our OSAS detection algorithm. The population under study was composed of subjects suspected of suffering from OSAS. A total of 214 SaO(2) signals were available. These signals were randomly divided into a training set (85 signals) and a test set (129 signals) to prospectively validate the proposed method. The OSAS detection algorithm achieved a diagnostic accuracy of 93.02% (97.00% sensitivity and 79.31% specificity) on the test set. It outperformed other alternative implementations that either use spectral and nonlinear features separately or are based on logistic regression (LR). The proposed method could be a useful tool to assist in early OSAS diagnosis, contributing to overcome the difficulties of conventional PSG.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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