The effect of angulation in abdominal aortic aneurysms: fluid-structure interaction simulations of idealized geometries.
Abdominal aortic aneurysm (AAA) represents a degenerative disease process of the abdominal aorta that results in dilation and permanent remodeling of the arterial wall. A fluid structure interaction (FSI) parametric study was conducted to evaluate the progression of aneurysmal disease and its possib...
| Publicado en: | Medical & Biological Engineering & Computing Vol. 48; no. 12; pp. 1175 - 1191 |
|---|---|
| Autores principales: | , , , , , , , , , , , , , , , |
| Formato: | Journal Article |
| Publicado: |
Springer Nature
Dec2010
|
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104569463&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104569463 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 01400118 PO0 jtl: Medical & Biological Engineering & Computing issn: 01400118 maglogo: N pubinfo: dt: Dec2010 vid: 48 iid: 12 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 104569463 NLM21088917 2010872584 10.1007/s11517-010-0714-y NLM21088917 104569463 ppf: 1175 ppct: 16 formats: fmt: @attributes: type: P tig: atl: The effect of angulation in abdominal aortic aneurysms: fluid-structure interaction simulations of idealized geometries. aug: au: Xenos M Alemu Y Zamfir D Einav S Ricotta JJ Labropoulos N Tassiopoulos A Bluestein D Xenos, Michalis Alemu, Yared Zamfir, Dan Einav, Shmuel Ricotta, John J Labropoulos, Nicos Tassiopoulos, Apostolos Bluestein, Danny affil: Department of Biomedical Engineering, Stony Brook University, Stony Brook, NY, USA sug: subj: Aortic Aneurysm, Abdominal Pathology Models, Biological Aged Aortic Aneurysm, Abdominal Physiopathology Aortic Aneurysm, Abdominal Radiography Aortic Rupture Pathology Aortic Rupture Physiopathology Blood Flow Velocity Physiology Iliac Artery Pathology Middle Age Blood Circulation Physiology Stress, Mechanical Tomography, X-Ray Computed Aged: 65+ years Middle Aged: 45-64 years ab: Abdominal aortic aneurysm (AAA) represents a degenerative disease process of the abdominal aorta that results in dilation and permanent remodeling of the arterial wall. A fluid structure interaction (FSI) parametric study was conducted to evaluate the progression of aneurysmal disease and its possible implications on risk of rupture. Two parametric studies were conducted using (i) the iliac bifurcation angle and (ii) the AAA neck angulation. Idealized streamlined AAA geometries were employed. The simulations were carried out using both isotropic and anisotropic wall material models. The parameters were based on CT scans measurements obtained from a population of patients. The results indicate that the peak wall stresses increased with increasing iliac and neck inlet angles. Wall shear stress (WSS) and fluid pressure were analyzed and correlated with the wall stresses for both sets of studies. An adaptation response of a temporary reduction of the peak wall stresses seem to correlate to a certain extent with increasing iliac angles. For the neck angulation studies it appears that a breakdown from symmetric vortices at the AAA inlet into a single larger vortex significantly increases the wall stress. Our parametric FSI study demonstrates the adaptation response during aneurysmal disease progression and its possible effects on the AAA risk of rupture. This dependence on geometric parameters of the AAA can be used as an additional diagnostic tool to help clinicians reach informed decisions in establishing whether a risky surgical intervention is warranted. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
|---|