Biological surface modification of titanium surfaces using glow discharge plasma.
To improve the biological activity of titanium, by using of glow discharge plasma (GDP), albumin-grafted titanium disk have been implemented and carefully studied. Titanium disks were pre-treated with GDP in an environment filled with argon and allylamine gas. Glutaraldehyde was used as a cross-link...
| Publicado en: | Medical & Biological Engineering & Computing Vol. 49; no. 6; pp. 701 - 707 |
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| Autores principales: | , , , , , , , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Springer Nature
Jun2011
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104572122&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104572122 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 01400118 PO0 jtl: Medical & Biological Engineering & Computing issn: 01400118 maglogo: N pubinfo: dt: Jun2011 vid: 49 iid: 6 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 104572122 NLM21286829 2011162620 10.1007/s11517-011-0742-2 NLM21286829 104572122 ppf: 701 ppct: 6 formats: fmt: @attributes: type: P tig: atl: Biological surface modification of titanium surfaces using glow discharge plasma. aug: au: Huang HM Hsieh SC Teng NC Feng SW Ou KL Chang WJ Huang, Haw-Ming Hsieh, Sung-Chih Teng, Nai-Chia Feng, Sheng-Wei Ou, Ken-Liang Chang, Wei-Jen affil: School of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei, Taiwan sug: subj: Biocompatible Materials Prostheses and Implants Titanium Cell Differentiation Human Materials Testing Methods Connective Tissue Cells Serum Albumin Surface Properties Tissue Engineering Methods ab: To improve the biological activity of titanium, by using of glow discharge plasma (GDP), albumin-grafted titanium disk have been implemented and carefully studied. Titanium disks were pre-treated with GDP in an environment filled with argon and allylamine gas. Glutaraldehyde was used as a cross-linking agent for albumin grafting. Then, the surface of the albumin-grafted titanium was examined using scanning electron microscopy and X-ray photoelectron spectroscopy. In addition, the static water contact angles of the albumin-grafted titanium disks were measured using goniometry. To observe the effects of albumin adsorption on cell behavior, MG-63 osteoblast-like cells were cultured on the surface-modified titanium disks. Blood coagulation resistance of the modified titanium was monitored and compared to the control titanium disks. The results demonstrated that MG-63 osteoblast-like cells cultured on the albumin-grafted titanium disks expressed better-differentiated morphology compare to cells grown on the control disks. Furthermore, albumin-grafting treatment significantly improved the surface wettability of the titanium disks and resulted in a significantly negative effect on thrombus formation. Based on these results, it was believed that the GDP can potentially improve the biofunctionality of titanium surfaces. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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