4D-MR flow analysis in patients after repair for tetralogy of Fallot.
Objectives: Comprehensive analysis of haemodynamics by 3D flow visualisation and retrospective flow quantification in patients after repair of tetralogy of Fallot (TOF).Methods: Time-resolved flow-sensitive 4D MRI (spatial resolution ~ 2.5 mm, temporal resolution = 38.4 ms) was acquired in ten patie...
| Published in: | European Radiology Vol. 21; no. 8; pp. 1651 - 1658 |
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| Main Authors: | , , , , , , , , , , , , , |
| Format: | research Journal Article |
| Published: |
Springer Nature
Aug2011
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104572903&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104572903 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09387994 NPH jtl: European Radiology issn: 09387994 maglogo: N pubinfo: dt: Aug2011 vid: 21 iid: 8 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 104572903 62001639 NLM21720942 2011194088 10.1007/s00330-011-2108-4 NLM21720942 104572903 ppf: 1651 ppct: 7 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: 4D-MR flow analysis in patients after repair for tetralogy of Fallot. aug: au: Geiger J Markl M Jung B Grohmann J Stiller B Langer M Arnold R Geiger, J Markl, M Jung, B Grohmann, J Stiller, B Langer, M Arnold, R affil: Department of Radiology, Medical Physics, University Hospital Freiburg, Hugstetter Str. 55, 79106 Freiburg, Germany sug: subj: Magnetic Resonance Imaging Methods Tetralogy of Fallot Physiopathology Tetralogy of Fallot Surgery Adolescence Blood Flow Velocity Case Control Studies Child Child, Preschool Female Hemodynamics Diagnostic Imaging Infant Male Young Adult Human Adolescent: 13-18 years Child: 6-12 years Child, Preschool: 2-5 years Infant: 1-23 months Female Male ab: Objectives: Comprehensive analysis of haemodynamics by 3D flow visualisation and retrospective flow quantification in patients after repair of tetralogy of Fallot (TOF).Methods: Time-resolved flow-sensitive 4D MRI (spatial resolution ~ 2.5 mm, temporal resolution = 38.4 ms) was acquired in ten patients after repair of TOF and in four healthy controls. Data analysis included the evaluation of haemodynamics in the aorta, the pulmonary trunk (TP) and left (lPA) and right (rPA) pulmonary arteries by 3D blood flow visualisation using particle traces, and quantitative measurements of flow velocity.Results: 3D visualisation of whole heart haemodynamics provided a comprehensive overview on flow pattern changes in TOF patients, mainly alterations in flow velocity, retrograde flow and pathological vortices. There was consistently higher blood flow in the rPA of the patients (rPA/lPA flow ratio: 2.6 ± 2.5 vs. 1.1 ± 0.1 in controls). Systolic peak velocity in the TP was higher in patients (1.9 m/s ± 0.7 m/s) than controls (0.9 m/s ± 0.1 m/s).Conclusions: 4D flow-sensitive MRI permits the comprehensive evaluation of blood flow characteristics in patients after repair of TOF. Altered flow patterns for different surgical techniques in the small patient cohort may indicate its value for patient monitoring and potentially identifying optimal surgical strategies. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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