A flexible framework for deriving assertions from electronic medical records.

Objective: This paper describes natural-language-processing techniques for two tasks: identification of medical concepts in clinical text, and classification of assertions, which indicate the existence, absence, or uncertainty of a medical problem. Because so many resources are available for process...

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Publicado en:Journal of the American Medical Informatics Association Vol. 18; no. 5; pp. 568 - 574
Autores principales: Roberts K, Harabagiu SM, Roberts, Kirk, Harabagiu, Sanda M
Formato: research Journal Article
Publicado: Oxford University Press / USA Sep2011
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Oxford University Press / USA
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        10.1136/amiajnl-2011-000152
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        atl: A flexible framework for deriving assertions from electronic medical records.
      aug:
        au:
          Roberts K
          Harabagiu SM
          Roberts, Kirk
          Harabagiu, Sanda M
        affil: Human Language Technology Research Institute, University of Texas at Dallas, Richardson, Texas 75080-0688, USA
      sug:
        subj:
          Data Mining Classification
          Decision Support Systems, Clinical Classification
          Electronic Health Records Classification
          Natural Language Processing
          Algorithms
          Semantics
          Uncertainty
      ab: Objective: This paper describes natural-language-processing techniques for two tasks: identification of medical concepts in clinical text, and classification of assertions, which indicate the existence, absence, or uncertainty of a medical problem. Because so many resources are available for processing clinical texts, there is interest in developing a framework in which features derived from these resources can be optimally selected for the two tasks of interest.Materials and Methods: The authors used two machine-learning (ML) classifiers: support vector machines (SVMs) and conditional random fields (CRFs). Because SVMs and CRFs can operate on a large set of features extracted from both clinical texts and external resources, the authors address the following research question: Which features need to be selected for obtaining optimal results? To this end, the authors devise feature-selection techniques which greatly reduce the amount of manual experimentation and improve performance.Results: The authors evaluated their approaches on the 2010 i2b2/VA challenge data. Concept extraction achieves 79.59 micro F-measure. Assertion classification achieves 93.94 micro F-measure.Discussion: Approaching medical concept extraction and assertion classification through ML-based techniques has the advantage of easily adapting to new data sets and new medical informatics tasks. However, ML-based techniques perform best when optimal features are selected. By devising promising feature-selection techniques, the authors obtain results that outperform the current state of the art.Conclusion: This paper presents two ML-based approaches for processing language in the clinical texts evaluated in the 2010 i2b2/VA challenge. By using novel feature-selection methods, the techniques presented in this paper are unique among the i2b2 participants.
      pubtype: Academic Journal
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      ougenre: Article
    language: English
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