Investigation of photoplethysmographic signals and blood oxygen saturation values obtained from human splanchnic organs using a fiber optic sensor.

Objective: A reliable, continuous method of monitoring splanchnic organ oxygen saturation could allow for the early detection of malperfusion, and may prevent the onset of multiple organ failure. Current monitoring techniques have not been widely accepted in critical care monitoring. As a preliminar...

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Publicado en:Journal of Clinical Monitoring & Computing Vol. 25; no. 4; pp. 245 - 256
Autores principales: Hickey M, Samuels N, Randive N, Langford RM, Kyriacou PA, Hickey, Michelle, Samuels, Neal, Randive, Nilesh, Langford, R M, Kyriacou, P A
Formato: research Journal Article
Publicado: Springer Nature Aug2011
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Aug2011
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      pub: Springer Nature
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        10.1007/s10877-011-9302-4
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        atl: Investigation of photoplethysmographic signals and blood oxygen saturation values obtained from human splanchnic organs using a fiber optic sensor.
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          Hickey M
          Samuels N
          Randive N
          Langford RM
          Kyriacou PA
          Hickey, Michelle
          Samuels, Neal
          Randive, Nilesh
          Langford, R M
          Kyriacou, P A
        affil: School of Engineering and Mathematical Sciences, City University London, Northampton Square, London, EC1V 0HB, UK
      sug:
        subj:
          Oximetry Equipment and Supplies
          Oxygen Blood
          Plethysmography Equipment and Supplies
          Splanchnic Circulation
          Adult
          Blood Gas Monitoring, Transcutaneous Equipment and Supplies
          Blood Gas Monitoring, Transcutaneous Methods
          Female
          Fingers
          Human
          Radiation, Non-Ionizing
          Laparotomy
          Male
          Middle Age
          Intraoperative Monitoring Equipment and Supplies
          Intraoperative Monitoring Methods
          Equipment and Supplies
          Oximetry Methods
          Plethysmography Methods
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Female
          Male
      ab: Objective: A reliable, continuous method of monitoring splanchnic organ oxygen saturation could allow for the early detection of malperfusion, and may prevent the onset of multiple organ failure. Current monitoring techniques have not been widely accepted in critical care monitoring. As a preliminary to developing a continuous indwelling device, this study evaluates a new handheld fiber optic photoplethysmographic (PPG) sensor for estimating the blood oxygen saturation (SpO(2)) of splanchnic organs during surgery.Methods: A fiber optic splanchnic PPG sensor, instrumentation system and virtual instrument were developed to facilitate PPG and SpO(2) measurement from splanchnic organs. Following Local Research Ethics Committee approval, the sensor was evaluated on seventeen ASA 1 and 2 patients undergoing open laparotomy. PPG signals were obtained from the large bowel, small bowel, liver and stomach. Simultaneous PPG signals from the finger were also obtained using an identical fiber optic sensor.Results: Good quality PPG signals with high signal-to-noise (SNR) ratios were obtained from all splanchnic sites under investigation. Analysis of the ac and dc amplitudes of the red and infrared PPG signals showed there to be a statistically significant difference between PPG signals obtained from splanchnic organs with those obtained from the finger (using fiber optic sensors). Estimated SpO(2) values from the splanchnic organs show good agreement with those obtained from the finger using both a fiber optic sensor and a commercial device. Furthermore, the results of a Bland and Altman analysis indicate that fiber optic splanchnic pulse oximetry, particularly of the bowel, may provide a suitable method for monitoring splanchnic organ perfusion.Conclusion: The evaluation of a new fiber optic sensor on anaesthetized patients undergoing laparotomy demonstrated that good quality PPG signals and SpO(2) estimates can be obtained from splanchnic organs. Such a sensor may provide a useful tool for the intraoperative assessment of splanchnic perfusion.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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