Pattern of BOLD signal in auditory cortex relates acoustic response to perceptual streaming.

Background: Segregating auditory scenes into distinct objects or streams is one of our brain's greatest perceptual challenges. Streaming has classically been studied with bistable sound stimuli, perceived alternately as a single group or two separate groups. Throughout the last decade different meth...

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Publicado en:BMC Neuroscience Vol. 12; no. 1; pp. 85 - 86
Autores principales: Hill, Kevin T, Bishop, Christopher W, Yadav, Deepak, Miller, Lee M
Formato: Journal Article
Publicado: BioMed Central 2011
Acceso en línea:Ver este registro en EBSCOhost
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      pub: BioMed Central
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        10.1186/1471-2202-12-85
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        atl: Pattern of BOLD signal in auditory cortex relates acoustic response to perceptual streaming.
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          Hill, Kevin T
          Bishop, Christopher W
          Yadav, Deepak
          Miller, Lee M
        affil: Center for Mind and Brain, University of California, 267 Cousteau Pl, Davis, California, 95616, USA. leemiller@ucdavis.edu.
      sug:
        subj:
          Auditory Cortex Physiology
          Auditory Perception Physiology
          Brain Mapping Methods
          Evoked Potentials, Auditory Physiology
          Female
          Human
          Male
          Young Adult
          Female
          Male
      ab: Background: Segregating auditory scenes into distinct objects or streams is one of our brain's greatest perceptual challenges. Streaming has classically been studied with bistable sound stimuli, perceived alternately as a single group or two separate groups. Throughout the last decade different methodologies have yielded inconsistent evidence about the role of auditory cortex in the maintenance of streams. In particular, studies using functional magnetic resonance imaging (fMRI) have been unable to show persistent activity within auditory cortex (AC) that distinguishes between perceptual states.Results: We use bistable stimuli, an explicit perceptual categorization task, and a focused region of interest (ROI) analysis to demonstrate an effect of perceptual state within AC. We find that AC has more activity when listeners perceive the split percept rather than the grouped percept. In addition, within this ROI the pattern of acoustic response across voxels is significantly correlated with the pattern of perceptual modulation. In a whole-brain exploratory test, we corroborate previous work showing an effect of perceptual state in the intraparietal sulcus.Conclusions: Our results show that the maintenance of auditory streams is reflected in AC activity, directly relating sound responses to perception, and that perceptual state is further represented in multiple, higher level cortical regions.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
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