Generation of realistic atrial to atrial interval series during atrial fibrillation.
The aim of the this study is to describe a methodological architecture for the generation of realistic atrial to atrial activation intervals (AA) during atrial fibrillation (AF), which can be used to investigate the role of the fibrillatory process in the ventricular response during AF. In this stud...
| Publicado en: | Medical & Biological Engineering & Computing Vol. 49; no. 11; pp. 1261 - 1269 |
|---|---|
| Autores principales: | , , , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Springer Nature
Nov2011
|
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104595291&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104595291 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 01400118 PO0 jtl: Medical & Biological Engineering & Computing issn: 01400118 maglogo: N pubinfo: dt: Nov2011 vid: 49 iid: 11 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 104595291 NLM21830052 2011349649 10.1007/s11517-011-0823-2 NLM21830052 104595291 ppf: 1261 ppct: 8 formats: fmt: @attributes: type: P tig: atl: Generation of realistic atrial to atrial interval series during atrial fibrillation. aug: au: Climent AM Atienza F Millet J Guillem MS Climent, Andreu M Atienza, Felipe Millet, Jose Guillem, Maria S affil: Bio-ITACA, Universitat Politecnica de Valencia, Camino de Vera sn, 46022 Valencia, Spain sug: subj: Atrial Fibrillation Physiopathology Signal Processing, Computer Assisted Atrioventricular Node Physiopathology Electrocardiography Methods Heart Atrium Physiopathology Heart Ventricle Physiopathology ab: The aim of the this study is to describe a methodological architecture for the generation of realistic atrial to atrial activation intervals (AA) during atrial fibrillation (AF), which can be used to investigate the role of the fibrillatory process in the ventricular response during AF. In this study, a methodology for the generation of AA interval series with a desired probability density function and autocorrelation function is presented. The methodology was evaluated on 2000 AA interval series from 20 endocardial recordings. The results showed that synthetic AA series presented the same statistical characteristics as the real AA series, with a correlation higher than 0.94 (P < 0.01) for all measured statistical parameters. In addition, the role of each statistical characteristic of the AA interval series in the ventricular response during AF is examined using a mathematical model of the atrioventricular node. The statistical characteristics of the AA series influenced the position of more probable RR intervals and the shape of the RR histogram, demonstrating the importance of an accurate characterization and generation of AA interval series during AF. The use of the present methodology may help in understanding the role of the atrial fibrillatory process in the ventricular response during AF. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
|---|