"ECG variability contour" method reveals amplitude changes in both ischemic patients and normal subjects during Dipyridamole stress: a preliminary report.
To detect and quantify consistent ECG amplitude changes, the "ECG variability contour" (EVC) method was proposed. Using this method we investigated amplitude changes in subjects undergoing myocardial perfusion imaging (MPI) with Dipyridamole (Dp). Fifty-three patients having reversible perfusion def...
| Publicado en: | Medical & Biological Engineering & Computing Vol. 49; no. 11; pp. 1311 - 1321 |
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| Autores principales: | , , , , , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Springer Nature
Nov2011
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104595300&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104595300 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 01400118 PO0 jtl: Medical & Biological Engineering & Computing issn: 01400118 maglogo: N pubinfo: dt: Nov2011 vid: 49 iid: 11 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 104595300 104595300 NLM21969223 2011349658 10.1007/s11517-011-0835-y NLM21969223 104595300 ppf: 1311 ppct: 10 formats: fmt: @attributes: type: P tig: atl: "ECG variability contour" method reveals amplitude changes in both ischemic patients and normal subjects during Dipyridamole stress: a preliminary report. aug: au: Dori G Gershinsky M Ben-Haim S Lewis BS Bitterman H Dori, Guy Gershinsky, Michal Ben-Haim, Simona Lewis, Basil S Bitterman, Haim affil: Department of Internal Medicine C, The Lady Davis Carmel Medical Center, Haifa, Israel sug: subj: Dipyridamole Diagnostic Use Electrocardiography Methods Myocardial Ischemia Diagnosis Signal Processing, Computer Assisted Vasodilator Agents Diagnostic Use Aged Aged, 80 and Over Female Prospective Studies Male Middle Age Heart Function Tests Methods Tomography, Emission-Computed, Single-Photon Methods Aged: 65+ years Aged, 80 & over Middle Aged: 45-64 years Female Male ab: To detect and quantify consistent ECG amplitude changes, the "ECG variability contour" (EVC) method was proposed. Using this method we investigated amplitude changes in subjects undergoing myocardial perfusion imaging (MPI) with Dipyridamole (Dp). Fifty-three patients having reversible perfusion defects and 19 normal subjects (NS) who were free of: perfusion defects on their MPI, standard ST-T changes during Dp stress, and a negative clinical follow up. Mean ∏¹(<∏¹>) was similar for the NS and patient group (6.2 ± 6.1 vs. 6.3 ± 6.2, P = 0.95). <∏¹> was 4.6 ± 3.0 in patients not having ST-T changes during Dp stress (n = 42), whereas in patients having ST-T changes (n = 11) it was 13.1 ± 10.2 (P < 0.001). For both groups <∏(QRS)> was smaller than <∏(ST)>, which in turn was smaller than <∏(T)>. The values of <∏(QRS)>, <∏(ST)>, and <∏(T)> for the NS, patients without and with ST-T changes were: 26.8 ± 28.6, 42.6 ± 41.8, 44.9 ± 36.5; 19.6 ± 20.8, 26.4 ± 31.4, 38.7 ± 27.3; 51.0 ± 30.0, 71.0 ± 36.8, 75.1 ± 20.9, respectively (P < 0.05 for all comparisons of patients with versus without ST-T changes). This study showed that Dp stress, with or without hypoperfusion, had a clear effect on myocyte electrophysiology, expressed by consistent ECG amplitude changes, detected by the EVC method. The EVC method did not distinguish between NS and patients in this clinical setting. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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