Quantification of airway deposition of intact and fragmented pollens.
Although pollen is one of the most widespread agents that can cause allergy, its airway transport and deposition is far from being fully explored. The objective of this study was to characterize the airway deposition of pollens and to contribute to the debate related to the increasing number of asth...
| Publicado en: | International Journal of Environmental Health Research Vol. 21; no. 6; pp. 427 - 441 |
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| Autores principales: | , , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Taylor & Francis Ltd
Dec2011
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104595697&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104595697 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09603123 57L jtl: International Journal of Environmental Health Research issn: 09603123 maglogo: Y pubinfo: dt: Dec2011 vid: 21 iid: 6 pid: 377 pub: Taylor & Francis Ltd place: Philadelphia, Pennsylvania artinfo: ui: 104595697 67043326 10.1080/09603123.2011.574269 NLM21563012 104595697 ppf: 427 ppct: 14 formats: fmt: @attributes: type: P tig: atl: Quantification of airway deposition of intact and fragmented pollens. aug: au: Horváth, Alpár Balásházy, Imre Farkas, Árpád Sárkány, Zoltán Hofmann, Werner Czitrovszky, Aladár Dobos, Erik affil: GlaxoSmithKline sug: subj: Pollen Adverse Effects Respiration Weather Adverse Effects Asthma Risk Factors Lung Computer Simulation Thorax Models, Statistical Correlational Studies Mathematics Age Factors Health Funding Source Quantitative Studies ab: Although pollen is one of the most widespread agents that can cause allergy, its airway transport and deposition is far from being fully explored. The objective of this study was to characterize the airway deposition of pollens and to contribute to the debate related to the increasing number of asthma attacks registered after thunderstorms. For the quantification of the deposition of inhaled pollens in the airways computer simulations were performed. Our results demonstrated that smaller and fragmented pollens may penetrate into the thoracic airways and deposit there, supporting the theory that fragmented pollen particles are responsible for the increasing incidence of asthma attacks following thunderstorms. Pollen deposition results also suggest that children are the most exposed to the allergic effects of pollens. Finally, pollens between 0.5 and 20 μm deposit more efficiently in the lung of asthmatics than in the healthy lung, especially in the bronchial region. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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