Patients with cervical cancer: why did screening not prevent these cases?

OBJECTIVE: The objective of the study was to assess the screening history of women with cervical cancer and review normal cervical smears 5 years preceding the diagnosis. STUDY DESIGN: Cytological and histological results of 401 women treated for invasive cervical cancer between 1991 and 2008 at the...

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Publicado en:American Journal of Obstetrics & Gynecology Vol. 205; no. 1; pp. 64.e1 - 641
Autores principales: de Bie RP, Vergers-Spooren HC, Massuger LF, Siebers AG, Salet-van der Pol MR, Vedder JE, Melchers WJ, Bulten J, Bekkers RL
Formato: research Journal Article
Publicado: Elsevier B.V. Jul2011
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jul2011
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        atl: Patients with cervical cancer: why did screening not prevent these cases?
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          de Bie RP
          Vergers-Spooren HC
          Massuger LF
          Siebers AG
          Salet-van der Pol MR
          Vedder JE
          Melchers WJ
          Bulten J
          Bekkers RL
        affil: Department of Obstetrics and Gynecology, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands.
      sug:
        subj:
          Carcinoma Epidemiology
          Early Detection of Cancer Statistics and Numerical Data
          Cervix Neoplasms Epidemiology
          Adult
          Carcinoma Diagnosis
          Carcinoma Prevention and Control
          Diagnostic Errors Statistics and Numerical Data
          Female
          Middle Age
          Netherlands
          Cervix Neoplasms Diagnosis
          Cervix Neoplasms Prevention and Control
          Cervical Smears
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Female
      ab: OBJECTIVE: The objective of the study was to assess the screening history of women with cervical cancer and review normal cervical smears 5 years preceding the diagnosis. STUDY DESIGN: Cytological and histological results of 401 women treated for invasive cervical cancer between 1991 and 2008 at the Radboud University Nijmegen Medical Center were studied. Ninety-eight normal smears were reviewed. RESULTS: Of the 401 women, 269 (67%) received at least 1 invitation for the national screening program for cervical cancer (NCSP). One- third fell outside the target age of the NCSP. Seventeen percent never responded to the invitation(s). Twenty-one percent had 1 or more normal smears within 5 years preceding the diagnosis. After review, only 39% of those smears were reviewed as a normal smear. CONCLUSION: Half of the women with cervical cancer were never screened because of the limited target age range or nonattendance. Twenty-one percent had a normal smear within 5 years preceding the diagnosis, caused by interpretation and/or sampling errors.
      pubtype: Academic Journal
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        research
        Journal Article
      ougenre: Article
    language: English
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