Sorbicins A and B, new urease and serine protease inhibitory triterpenes from Sorbus cashmiriana.

Two new lupene-type triterpenes, sorbicins A (1) and B (2), have been isolated from the chloroform-soluble fraction of the MeOH extract from the whole plant of Sorbus cashmiriana, and their structures were elucidated by spectroscopic techniques including 2D NMR. Both compounds displayed urease and α...

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Publicado en:Journal of Asian Natural Products Research Vol. 13; no. 12; pp. 1081 - 1087
Autores principales: Kazmi, Mehdi Hassan, Fatima, Itrat, Malik, Abdul, Iqbal, Lubna, Latif, Mehreen, Afza, Nighat
Formato: pictorial research tables/charts Journal Article
Publicado: Taylor & Francis Ltd Dec2011
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Dec2011
      vid: 13
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      pub: Taylor & Francis Ltd
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        atl: Sorbicins A and B, new urease and serine protease inhibitory triterpenes from Sorbus cashmiriana.
      aug:
        au:
          Kazmi, Mehdi Hassan
          Fatima, Itrat
          Malik, Abdul
          Iqbal, Lubna
          Latif, Mehreen
          Afza, Nighat
        affil: Department of Applied Chemistry, University of Karachi, Pakistan
      sug:
        subj:
          Hydrocarbons Analysis
          Plant Extracts Analysis
          Plants, Medicinal Analysis
          Urease Antagonists and Inhibitors
          Protease Inhibitors Analysis
          Peptide Hydrolases Analysis
          Correlational Studies
          Magnetic Resonance Spectroscopy
          Powders Analysis
          Spectrophotometry
          Chromatography, Thin Layer
          Chromatography
          In Vitro Studies
          Biological Assay
          Descriptive Statistics
          Data Analysis Software
      ab: Two new lupene-type triterpenes, sorbicins A (1) and B (2), have been isolated from the chloroform-soluble fraction of the MeOH extract from the whole plant of Sorbus cashmiriana, and their structures were elucidated by spectroscopic techniques including 2D NMR. Both compounds displayed urease and α-chymotrypsin inhibitory potential.
      pubtype: Academic Journal
      doctype:
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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