Diagnostic values of Helicobacter pylori diagnostic tests: stool antigen test, urea breath test, rapid urease test, serology and histology.
BACKGROUND: The purpose of this study is to compare validity of 5 diagnostic tests of helicobacter pylori with each other: stool antigen test, urea breath test (UBT), rapid urease test (RUT), serology and histology. METHODS: A total of 94 patients who had indication of endoscopy entered the study. A...
| Publicado en: | Journal of Research in Medical Sciences Vol. 16; no. 9; pp. 1097 - 1105 |
|---|---|
| Autores principales: | , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Wolters Kluwer India Pvt Ltd
Sep2011
|
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104610305&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104610305 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 17351995 785C jtl: Journal of Research in Medical Sciences issn: 17351995 maglogo: N pubinfo: dt: Sep2011 vid: 16 iid: 9 pid: 16919 pub: Wolters Kluwer India Pvt Ltd artinfo: ui: 104610305 104610305 2011397922 NLM22973378 PMC3430034 104610305 ppf: 1097 ppct: 8 formats: tig: atl: Diagnostic values of Helicobacter pylori diagnostic tests: stool antigen test, urea breath test, rapid urease test, serology and histology. aug: au: Kazemi, Shadi Tavakkoli, Hamid Habibzadeh, Mohamad Reza Emami, Mohammad Hassan affil: Internal Medicine Resident, Department of Internal Medicine, Isfahan University of Medical Sciences, Isfahan, Iran. sug: subj: Antigens Analysis Diagnosis, Laboratory Methods Enzymes Analysis Feces Analysis Helicobacter Infections Diagnosis Urea Analysis Adult Aged Confidence Intervals Data Analysis Software Descriptive Statistics Endoscopy False Positive Results Female Human Male Middle Age Outpatients Predictive Value of Tests ROC Curve Sensitivity and Specificity Adult: 19-44 years Aged: 65+ years Middle Aged: 45-64 years Female Male ab: BACKGROUND: The purpose of this study is to compare validity of 5 diagnostic tests of helicobacter pylori with each other: stool antigen test, urea breath test (UBT), rapid urease test (RUT), serology and histology. METHODS: A total of 94 patients who had indication of endoscopy entered the study. All of the 5 tests were performed for each patient. When the results of at least 2 tests were positive (except serology), Helicobacter pylori infection was considered to be positive. The sensitivity, specificity, positive predictive value, negative predictive value, accuracy and area under receiver operating characteristic (ROC) curve of these 5 tests were determined. RESULTS: The sensitivity, specificity, positive predictive value, negative predictive value, accuracy and area under ROC curve of these 5 tests are as below, respectively. Histology: 89%, 78%, 93%, 91%, 85% and 0.881; RUT: 93%, 75%, 95%, 94%, 86% and 0.831; serology: 50%, 54%, 46%, 61%, 52% and 0.563; stool antigen test: 96%, 83%, 98%, 96%, 91% and 0.897; UBT: 89%, 73%, 92%, 90%, 82% and 0.892. CONCLUSIONS: Stool antigen test is the most accurate test for Helicobacter pylori diagnosis before eradication of these bacteria. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
|---|