Cancer-related symptom clusters for symptom management in outpatients after commencing adjuvant chemotherapy, at 6 months, and 12 months.
Goals Of Work: The aim of this secondary data analysis was to investigate symptom clusters over time for symptom management of a patient group after commencing adjuvant chemotherapy.Materials and Methods: A prospective longitudinal study of 219 cancer outpatients conducted within 1 month of commenci...
| Publicado en: | Supportive Care in Cancer Vol. 20; no. 1; pp. 95 - 106 |
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| Autores principales: | , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Springer Nature
Jan2012
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104616950&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104616950 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09414355 O1J jtl: Supportive Care in Cancer issn: 09414355 maglogo: N pubinfo: dt: Jan2012 vid: 20 iid: 1 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 104616950 67449309 NLM21293884 2011407509 10.1007/s00520-010-1070-z NLM21293884 104616950 ppf: 95 ppct: 11 formats: fmt: @attributes: type: P tig: atl: Cancer-related symptom clusters for symptom management in outpatients after commencing adjuvant chemotherapy, at 6 months, and 12 months. aug: au: Skerman HM Yates PM Battistutta D Skerman, Helen M Yates, Patsy M Battistutta, Diana affil: Institute of Health and Biomedical Innovation (IHBI), Queensland University of Technology (QUT), 60 Musk Avenue, Kelvin Grove, QLD, 4059, Australia sug: subj: Antineoplastic Agents Therapeutic Use Neoplasms Physiopathology Outpatients Adolescence Adult Aged Chemotherapy, Adjuvant Methods Cluster Analysis Disorders of Excessive Somnolence Epidemiology Disorders of Excessive Somnolence Etiology Factor Analysis Fatigue Etiology Female Human Prospective Studies Male Middle Age Neoplasms Drug Therapy Time Factors Young Adult Adolescent: 13-18 years Adult: 19-44 years Aged: 65+ years Middle Aged: 45-64 years Female Male ab: Goals Of Work: The aim of this secondary data analysis was to investigate symptom clusters over time for symptom management of a patient group after commencing adjuvant chemotherapy.Materials and Methods: A prospective longitudinal study of 219 cancer outpatients conducted within 1 month of commencing chemotherapy (T1), 6 months (T2), and 12 months (T3) later. Patients' distress levels were assessed for 42 physical symptoms on a clinician-modified Rotterdam Symptom Checklist. Symptom clusters were identified in exploratory factor analyses at each time. Symptom inclusion in clusters was determined from structure coefficients. Symptoms could be associated with multiple clusters. Stability over time was determined from symptom cluster composition and the proportion of symptoms in the initial symptom clusters replicated at later times.Main Results: Fatigue and daytime sleepiness were the most prevalent distressing symptoms over time. The median number of concurrent distressing symptoms approximated 7, over time. Five consistent clusters were identified at T1, T2, and T3. An additional two clusters were identified at 12 months, possibly due to less variation in distress levels. Weakness and fatigue were each associated with two, four, and five symptom clusters at T1, T2, and T3, respectively, potentially suggesting different causal mechanisms.Conclusion: Stability is a necessary attribute of symptom clusters, but definitional clarification is required. We propose that a core set of concurrent symptoms identifies each symptom cluster, signifying a common cause. Additional related symptoms may be included over time. Further longitudinal investigation is required to identify symptom clusters and the underlying causes. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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