Determination of Digoxin Clearance in Japanese Elderly Patients for Optimization of Drug Therapy A Population Pharmacokinetics Analysis Using Nonlinear Mixed-Effects Modelling.
Background: Optimal use of digoxin in the elderly population requires information about the drug's pharmacokinetics and the influence of various factors on the drug's disposition. However, because of sampling restrictions, it is often difficult to perform traditional pharmacokinetic studies in elder...
| Publicado en: | Drugs & Aging Vol. 28; no. 10; pp. 831 - 842 |
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| Autores principales: | , , , , , , |
| Formato: | equations & formulas research tables/charts Journal Article |
| Publicado: |
Springer Nature
2011
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| Acceso en línea: | Ver este registro en EBSCOhost |