The VITROS Immunodiagnostics Products Anti-HIV 1+2 Assay: A Rapid and Reliable Method for HIV Screening.

Background: To ensure increased awareness of HIV status by patients, the Centers for Disease Control and Prevention (CDC) has issued new guidelines that greatly expand screening recommendations. The goal of the present study was to assess the overall reliability, sensitivity, specificity, and turnar...

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Publicado en:Laboratory Medicine Vol. 42; no. 4; pp. 209 - 213
Autores principales: Thompson, Matthew P., Hidalgo, Darnely, Kim, Anne, Ansari, M. Qasim
Formato: research tables/charts Journal Article
Publicado: Oxford University Press / USA Apr2011
Acceso en línea:Ver este registro en EBSCOhost
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        atl: The VITROS Immunodiagnostics Products Anti-HIV 1+2 Assay: A Rapid and Reliable Method for HIV Screening.
      aug:
        au:
          Thompson, Matthew P.
          Hidalgo, Darnely
          Kim, Anne
          Ansari, M. Qasim
        affil: Department of Pathology, University of Texas Southwestern Medical Center, Parkland Memorial Hospital, Dallas, TX
      sug:
        subj:
          AIDS Serodiagnosis Methods
          Health Screening
          Reagent Kits, Diagnostic Evaluation
          Human
          Comparative Studies
          Turnaround Time
          Chemiluminescent Measurements
          Sensitivity and Specificity
          False Negative Results
          False Positive Results
          Evaluation Research
          Hospitals, Community
          Autoanalyzers
      ab: Background: To ensure increased awareness of HIV status by patients, the Centers for Disease Control and Prevention (CDC) has issued new guidelines that greatly expand screening recommendations. The goal of the present study was to assess the overall reliability, sensitivity, specificity, and turnaround time (TAT) of the VITROS Anti-HIV 1+2 Assay (Ortho Clinical Diagnostics, Rochester, NY) in a large community hospital setting. The assay was recently approved by the Food and Drug Administration (FDA). Methods: We compared our current Abbott HIVAB assay (Abbott Laboratories, Abbott Park, IL) with how the VITROS performed on the random access VITROS ECi/ECiQ System in a head-to-head comparison of 298 patient samples and a retrospective comparison of TAT over an 8-month period of utilization.Results: Our data indicate that the VITROS is as sensitive (100%, n=298) and more specific (98% vs 83%) than the Abbott HIVAB and has a faster average TAT (156 minutes vs 1266 minutes). Conclusions: Use of this rapid and reliable assay will lead to greater awareness of HIV status and, hopefully, a decrease in incidence of HIV disease.
      pubtype: Academic Journal
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        research
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      ougenre: Article
    language: English
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