Biplane Correlation Imaging: A Feasibility Study Based on Phantom and Human Data.

The objective of this study was to implement and evaluate the performance of a biplane correlation imaging (BCI) technique aimed to reduce the effect of anatomic noise and improve the detection of lung nodules in chest radiographs. Seventy-one low-dose posterior-anterior images were acquired from an...

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Publicado en:Journal of Digital Imaging Vol. 25; no. 1; pp. 137 - 148
Autores principales: Samei, Ehsan, Majdi-Nasab, Nariman, Dobbins, James, McAdams, H.
Formato: diagnostic images pictorial research tables/charts Journal Article
Publicado: Springer Nature Feb2012
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Feb2012
      vid: 25
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      pub: Springer Nature
      place: New York, New York
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        atl: Biplane Correlation Imaging: A Feasibility Study Based on Phantom and Human Data.
      aug:
        au:
          Samei, Ehsan
          Majdi-Nasab, Nariman
          Dobbins, James
          McAdams, H.
        affil: Carl E. Ravin Advanced Imaging Laboratories, Department of Radiology, Duke University, Durham 27710 USA
      sug:
        subj:
          Diagnosis, Computer Assisted
          Radiography, Thoracic
          Lung Pathology
          Diagnostic Imaging Methods
          Human
          Prospective Studies
          Phantoms, Imaging
          Data Analysis Software
          Adult
          Middle Age
          Aged
          Female
          Male
          Radiographic Image Interpretation, Computer-Assisted
          Funding Source
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Aged: 65+ years
          Female
          Male
      ab: The objective of this study was to implement and evaluate the performance of a biplane correlation imaging (BCI) technique aimed to reduce the effect of anatomic noise and improve the detection of lung nodules in chest radiographs. Seventy-one low-dose posterior-anterior images were acquired from an anthropomorphic chest phantom with 0.28° angular separations over a range of ±10° along the vertical axis within an 11 s interval. Similar data were acquired from 19 human subjects with institutional review board approval and informed consent. The data were incorporated into a computer-aided detection (CAD) algorithm in which suspect lesions were identified by examining the geometrical correlation of the detected signals that remained relatively constant against variable anatomic backgrounds. The data were analyzed to determine the effect of angular separation, and the overall sensitivity and false-positives for lung nodule detection. The best performance was achieved for angular separations of the projection pairs greater than 5°. Within that range, the technique provided an order of magnitude decrease in the number of false-positive reports when compared with CAD analysis of single-view images. Overall, the technique yielded ~1.1 false-positive per patient with an average sensitivity of 75%. The results indicated that the incorporation of angular information can offer a reduction in the number of false-positives without a notable reduction in sensitivity. The findings suggest that the BCI technique has the potential for clinical implementation as a cost-effective technique to improve the detection of subtle lung nodules with lowered rate of false-positives.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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