Detection of Cancerous Masses in Mammograms by Template Matching: Optimization of Template Brightness Distribution by Means of Evolutionary Algorithm.

Optimization of brightness distribution in the template used for detection of cancerous masses in mammograms by means of correlation coefficient is presented. This optimization is performed by the evolutionary algorithm using an auxiliary mass classifier. Brightness along the radius of the circularl...

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Publicado en:Journal of Digital Imaging Vol. 25; no. 1; pp. 162 - 173
Autores principales: Bator, Marcin, Nieniewski, Mariusz
Formato: diagnostic images research tables/charts Journal Article
Publicado: Springer Nature Feb2012
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Feb2012
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      pub: Springer Nature
      place: New York, New York
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        atl: Detection of Cancerous Masses in Mammograms by Template Matching: Optimization of Template Brightness Distribution by Means of Evolutionary Algorithm.
      aug:
        au:
          Bator, Marcin
          Nieniewski, Mariusz
        affil: Faculty of Applied Informatics and Mathematics, Warsaw University of Life Sciences, ul. Nowoursynowska 159 02776 Warsaw Poland
      sug:
        subj:
          Mammography
          Breast Neoplasms Diagnosis
          Diagnosis, Computer Assisted
          Human
          ROC Curve
          Algorithms
          False Positive Results
          Confidence Intervals
          Evaluation Research
      ab: Optimization of brightness distribution in the template used for detection of cancerous masses in mammograms by means of correlation coefficient is presented. This optimization is performed by the evolutionary algorithm using an auxiliary mass classifier. Brightness along the radius of the circularly symmetric template is coded indirectly by its second derivative. The fitness function is defined as the area under curve (AUC) of the receiver operating characteristic (ROC) for the mass classifier. The ROC and AUC are obtained for a teaching set of regions of interest (ROIs), for which it is known whether a ROI is true-positive (TP) or false-positive (F). The teaching set is obtained by running the mass detector using a template with a predetermined brightness. Subsequently, the evolutionary algorithm optimizes the template by classifying masses in the teaching set. The optimal template (OT) can be used for detection of masses in mammograms with unknown ROIs. The approach was tested on the training and testing sets of the Digital Database for Screening Mammography (DDSM). The free-response receiver operating characteristic (FROC) obtained with the new mass detector seems superior to the FROC for the hemispherical template (HT). Exemplary results are the following: in the case of the training set in the DDSM, the true-positive fraction (TPF) = 0.82 for the OT and 0.79 for the HT; in the case of the testing set, TPF = 0.79 for the OT and 0.72 for the HT. These values were obtained for disease cases, and the false-positive per image (FPI) = 2.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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