Thromboprophylaxis following major skeletal trauma: a systematic review.
Purpose: Venous thromboembolic disease following skeletal polytrauma is a major issue for trauma surgeons, but there is no consensus of opinion regarding the optimal form of prophylaxis. The purpose of this paper was to compare the incidence of venous thromboembolic events (VTE) after major skeletal...
| Publicado en: | European Journal of Trauma & Emergency Surgery Vol. 37; no. 5; pp. 479 - 491 |
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| Autores principales: | , , |
| Formato: | research systematic review tables/charts Journal Article |
| Publicado: |
Springer Nature
Oct2011
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104635386&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104635386 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 18639933 3C05 jtl: European Journal of Trauma & Emergency Surgery issn: 18639933 maglogo: N pubinfo: dt: Oct2011 vid: 37 iid: 5 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 104635386 66846818 10.1007/s00068-010-0065-2 104635386 ppf: 479 ppct: 12 formats: fmt: @attributes: type: P tig: atl: Thromboprophylaxis following major skeletal trauma: a systematic review. aug: au: Smith, T. Taylor, R. Hing, C. affil: School of Allied Health Professions, University of East Anglia, Norwich NR4 7TJ UK sug: subj: Thrombosis Prevention and Control Premedication Skeleton Injuries Human Systematic Review Venous Thrombosis Risk Factors CINAHL Database Cochrane Library Embase Medline Spinal Fractures Complications Spinal Cord Injuries Complications Aging Pelvic Fractures Complications Compression Garments Anticoagulants Data Analysis Software ab: Purpose: Venous thromboembolic disease following skeletal polytrauma is a major issue for trauma surgeons, but there is no consensus of opinion regarding the optimal form of prophylaxis. The purpose of this paper was to compare the incidence of venous thromboembolic events (VTE) after major skeletal trauma managed with different prophylactic methods and their combinations. Methods: A search of AMED, CINAHL, Cochrane Library, EMBASE and MEDLINE databases was performed from their inception to July 2010. A search of unpublished literature databases was undertaken. All randomised controlled trials assessing the incidence of VTE events between two or more forms of thromboprophylaxis for patient following major skeletal trauma were included. Two reviewers independently identified all eligible articles, extracted the data, and critically appraised all included publications using the Critical Appraisal Skills Programme tool. Results: A total of 11 papers were identified. The findings of this study suggest that low molecular weight heparin (LMWH) may be superior to low dose heparin (LDH), and that LMWH should be used in addition to mechanical prophylaxis measures in patients following major skeletal trauma. There is limited evidence for the use of electrostimulation. There appeared to be no significant difference between the use of LDH compared to calf compression devices. However, the evidence-base was insufficient in both size and methodological quality. Conclusions: There is currently insufficient research to be able to inform trauma surgeons as to the optimal method of thromboprophylaxis for patients following major skeletal trauma. pubtype: Academic Journal doctype: research systematic review tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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