Completely automated robust edge snapper for carotid ultrasound IMT measurement on a multi-institutional database of 300 images.

The carotid intima-media thickness (IMT) is the most used marker for the progression of atherosclerosis and onset of cardiovascular diseases. Computer-aided measurements improve accuracy and precision, but usually require user interaction. In this paper we characterized a new and completely automate...

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Publicado en:Medical & Biological Engineering & Computing Vol. 49; no. 8; pp. 935 - 946
Autores principales: Molinari F, Rajendra Acharya U, Zeng G, Meiburger KM, Suri JS, Molinari, Filippo, Rajendra Acharya, U, Zeng, Guang, Meiburger, Kristen M, Suri, Jasjit S
Formato: research Journal Article
Publicado: Springer Nature Aug2011
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Aug2011
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      pub: Springer Nature
      place: New York, New York
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        atl: Completely automated robust edge snapper for carotid ultrasound IMT measurement on a multi-institutional database of 300 images.
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        au:
          Molinari F
          Rajendra Acharya U
          Zeng G
          Meiburger KM
          Suri JS
          Molinari, Filippo
          Rajendra Acharya, U
          Zeng, Guang
          Meiburger, Kristen M
          Suri, Jasjit S
        affil: Biolab, Dipartimento di Elettronica, Politecnico di Torino, Corso Duca degli Abruzzi, 24, 10129 Turin, Italy
      sug:
        subj:
          Carotid Arteries Ultrasonography
          Carotid Artery Diseases Ultrasonography
          Image Interpretation, Computer Assisted Methods
          Blood Vessels Ultrasonography
          Muscle, Smooth Ultrasonography
          Adult
          Aged
          Aged, 80 and Over
          Carotid Arteries Pathology
          Carotid Artery Diseases Pathology
          Human
          Middle Age
          Radiology Information Systems
          Blood Vessels Pathology
          Muscle, Smooth Pathology
          Adult: 19-44 years
          Aged: 65+ years
          Aged, 80 & over
          Middle Aged: 45-64 years
      ab: The carotid intima-media thickness (IMT) is the most used marker for the progression of atherosclerosis and onset of cardiovascular diseases. Computer-aided measurements improve accuracy and precision, but usually require user interaction. In this paper we characterized a new and completely automated technique for carotid segmentation and IMT measurement based on the merits of two previously developed techniques. We used an integrated approach of intelligent image feature extraction and line fitting for automatically locating the carotid artery in the image frame, followed by wall interfaces extraction based on a Gaussian edge operator. We called our system-CARES. We validated CARES on a multi-institutional database of 300 carotid ultrasound images. The IMT measurement bias was 0.032 ± 0.141 mm. Our novel approach of CARES processed 96% of the images in the database taken from two different institutions. In order to evaluate its performance, the figure-of-merit (FoM) was defined as the percent ratio between the average IMT computed by CARES and the one obtained from manual tracings by expert sonographers. The estimated FoM by CARES was 95.7%. Comparing the IMT bias of CARES with our previously published method CALEX that showed an IMT bias equal to 0.099 ± 0.137 mm, CARES improved the IMT accuracy by 67%, while increasing the standard deviation by 3%. CARES could be a useful research tool for processing large datasets in multi-center studies involving atherosclerosis.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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