Physiologic Determinants of Left Ventricular Systolic Torsion Assessed by Speckle Tracking Echocardiography in Healthy Subjects.
Background: The associations of left ventricular (LV) systolic torsion with clinical and echocardiographic variables in physiological conditions have not been fully investigated. We explored the independent determinants of LV systolic torsion in a population of normal subjects. Methods: In 119 healt...
| Published in: | Echocardiography Vol. 28; no. 6; pp. 641 - 649 |
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| Main Authors: | , , , , , |
| Format: | research tables/charts Journal Article |
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Wiley-Blackwell
Jul2011
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104664771&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104664771 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 07422822 GSE jtl: Echocardiography issn: 07422822 maglogo: Y pubinfo: dt: Jul2011 vid: 28 iid: 6 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 104664771 62977688 10.1111/j.1540-8175.2011.01406.x NLM21771053 104664771 ppf: 641 ppct: 8 formats: fmt: @attributes: type: P tig: atl: Physiologic Determinants of Left Ventricular Systolic Torsion Assessed by Speckle Tracking Echocardiography in Healthy Subjects. aug: au: Cameli, Matteo Ballo, Piercarlo Righini, Francesca Maria Caputo, Maria Lisi, Matteo Mondillo, Sergio affil: Department of Cardiovascular Diseases, University of Siena, Italy sug: subj: Torsion Abnormality Ultrasonography Echocardiography Methods Heart Physiology Human Step-Wise Multiple Regression Male Female Sex Factors Age Factors Heart Ventricle, Left Ultrasonography Heart Ventricle, Left Physiology Reproducibility of Results Intraclass Correlation Coefficient Descriptive Statistics Pearson's Correlation Coefficient Multivariate Analysis Data Analysis Software Multiple Regression Adult Middle Age Adult: 19-44 years Middle Aged: 45-64 years Male Female ab: Background: The associations of left ventricular (LV) systolic torsion with clinical and echocardiographic variables in physiological conditions have not been fully investigated. We explored the independent determinants of LV systolic torsion in a population of normal subjects. Methods: In 119 healthy subjects, peak twist angle (LVtw) and torsion (LVtor) during ejection, and the QRS-LVtw interval (time-to-peak LVtw) were measured by speckle tracking. LV twisting rate and rotational deformation delay were also determined. Results: Stepwise multiple regression showed that LVtw was independently associated with indexed end-systolic volume (β = –0.200, P < 0.0001), peak early diastolic mitral annulus velocity (β = –0.186, P = 0.0001), heart rate (β = 0.178, P = 0.0003), and male gender (β = –0.174, P = 0.0004). Similar results were found for LVtor. Age was the only parameter, which has demonstrated an independent correlation with time-to-peak LVtw (β = 0.329, P < 0.0001). Despite significance of these associations, the proportions of variability explained by regression models were relatively low (range 11–26%), and no accurate predictive models were identifiable for LV twisting rate and rotational deformation delay. Conclusion: In normal individuals, indexed end-systolic LV volume, LV relaxation, heart rate, gender, and age correlate independently with LV torsion mechanics. However, conventional echocardiographic and clinical variables are not able to predict LV torsion mechanics. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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