Automating the process of critical appraisal and assessing the strength of evidence with information extraction technology.

Background Critical appraisal, one of the most crucial steps in the practice of evidence-based medicine, is expertise-dependent and time-consuming. The objective of this study was to develop and evaluate an automated text-mining system that could determine the evidence level provided by a medical ar...

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Publicado en:Journal of Evaluation in Clinical Practice Vol. 17; no. 4; pp. 832 - 839
Autores principales: Lin, Jou-Wei, Chang, Chia-Hsuin, Lin, Ming-Wei, Ebell, Mark H., Chiang, Jung-Hsien
Formato: research tables/charts Journal Article
Publicado: Wiley-Blackwell Aug2011
Acceso en línea:Ver este registro en EBSCOhost
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        10.1111/j.1365-2753.2011.01712.x
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        atl: Automating the process of critical appraisal and assessing the strength of evidence with information extraction technology.
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        au:
          Lin, Jou-Wei
          Chang, Chia-Hsuin
          Lin, Ming-Wei
          Ebell, Mark H.
          Chiang, Jung-Hsien
        affil: Attending Cardiologist, Cardiovascular Center, National Taiwan University Hospital Yun-Lin Branch, Dou-Liou City, Taiwan and Associate Professor, Department of Medicine, National Taiwan University College of Medicine and Hospital, Taipei, Taiwan
      sug:
        subj:
          Abstracting and Indexing Methods
          Medical Practice, Evidence-Based
          Information Retrieval
          Data Analysis, Computer Assisted
          Human
          Decision Trees Utilization
          Neural Networks (Computer) Utilization
          Data Mining
          Study Design
          Cardiovascular Diseases
          Confidence Intervals
          Relative Risk
          Odds Ratio
          Funding Source
      ab: Background Critical appraisal, one of the most crucial steps in the practice of evidence-based medicine, is expertise-dependent and time-consuming. The objective of this study was to develop and evaluate an automated text-mining system that could determine the evidence level provided by a medical article. Methods A text processor was designed and built to interpret the abstracts of medical literature. The system extracted information about: (1) the impact factor of the journal; (2) study design; (3) human subject involvement; (4) number of subjects; (5) P-value; and (6) confidence intervals. We used a classification tree algorithm (C4.5) to create a decision tree using supervised classification. Each article was categorized into evidence level A, B or C, and the output was compared to that determined by domain experts (the reference standard). Results We used a corpus of 3180 cardiovascular disease original research articles, of which 1108 were previously assigned evidence level A, 1705 level B and 367 level C by domain experts. The abstracts were analysed by our automated system and an evidence level was assigned. The algorithm accurately classified 85% of the articles. The agreement between computer and domain experts was substantial ( κ-value: 0.78). Cross-validation showed consistent results across repeated tests. Conclusion The automated engine accurately classified the evidence level. Misclassification might have resulted from incomplete information retrieval and inaccurate data extraction. Further efforts will focus on assessing relevance and using additional study design features to refine evidence level classification.
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      ougenre: Article
    language: English
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