Quantitative Measurement of Circumferential Carotid Arterial Strain by Two-Dimensional Speckle Tracking Imaging in Healthy Subjects.

Background: Two-dimensional speckle tracking imaging (2DS) enables quantitative measurement of left ventricular strain. However, application of 2DS for measurement of circumferential carotid arterial strain (CAS) is not fully elucidated. We investigated the feasibility and reproducibility of measuri...

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Publicado en:Echocardiography Vol. 28; no. 8; pp. 899 - 907
Autores principales: Yuda, Satoshi, Kaneko, Reiko, Muranaka, Atsuko, Hashimoto, Akiyoshi, Tsuchihashi, Kazufumi, Miura, Tetsuji, Watanabe, Naoki, Shimamoto, Kazuaki
Formato: diagnostic images research tables/charts tracings Journal Article
Publicado: Wiley-Blackwell Sep2011
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Sep2011
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        atl: Quantitative Measurement of Circumferential Carotid Arterial Strain by Two-Dimensional Speckle Tracking Imaging in Healthy Subjects.
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        au:
          Yuda, Satoshi
          Kaneko, Reiko
          Muranaka, Atsuko
          Hashimoto, Akiyoshi
          Tsuchihashi, Kazufumi
          Miura, Tetsuji
          Watanabe, Naoki
          Shimamoto, Kazuaki
        affil: Department of Clinical Laboratory Medicine; Second Department of Internal Medicine, Sapporo Medical University School of Medicine, Sapporo, Japan
      sug:
        subj:
          Carotid Arteries Ultrasonography
          Echocardiography Methods
          Human
          Male
          Female
          Descriptive Statistics
          Young Adult
          Adult
          Reproducibility of Results
          Multiple Regression
          Middle Age
          Blood Pressure Physiology
          Data Analysis Software
          Univariate Statistics
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Male
          Female
      ab: Background: Two-dimensional speckle tracking imaging (2DS) enables quantitative measurement of left ventricular strain. However, application of 2DS for measurement of circumferential carotid arterial strain (CAS) is not fully elucidated. We investigated the feasibility and reproducibility of measuring CAS by 2DS and determinants of CAS in healthy subjects. Methods: Fifty-one healthy subjects (20 men and 31 women) with a mean age of 29 ± 11 years were enrolled. Ultrasound examination of bilateral common carotid arteries (CCAs) was performed and short axial views were recorded. The mean intima-media thickness (IMT) of bilateral CCAs was measured using semiautomated edge-detection software. Bilateral peak CAS at systole and time to peak CAS in each region were measured by 2DS. Stiffness parameter β of bilateral CCAs was measured and bilateral cardio-ankle vascular index (CAVI) was recorded. Intraobserver and interobserver variabilities for mean CAS were calculated in 15 subjects. Results: Of the 612 regions, 577 (94%) had adequate waveforms for measurement of CAS. The mean value of CAS was 6.7 ± 2.1%. Required time for CAS analysis was 128 ± 12 seconds per subject. Multiple regression analysis identified age (P < 0.001) and pulse pressure (P < 0.05) as independent significant determinants of mean CAS. Corrected CAS, which was calculated as mean CAS/pulse pressure, correlated with age, mean IMT, and stiffness parameter β and systolic pressure (P < 0.001), age (P < 0.01), and stiffness parameter β (P = 0.02) were identified as independent significant determinants of corrected CAS. Coefficient of variance (CV) of intraobserver and interobserver variabilities for mean CAS were 8.8% and 5.9%, respectively. Conclusions: 2DS in the CCAs is simply and quickly performed with high feasibility and excellent reproducibility. In healthy subjects, age and pulse pressure are the most important determinants of mean CAS. (Echocardiography 2011;28:899-906)
      pubtype: Academic Journal
      doctype:
        diagnostic images
        research
        tables/charts
        tracings
        Journal Article
      ougenre: Article
    language: English
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