Pain-related cerebral activation is altered by a distracting cognitive task.
It has previously been suggested that the activity in sensory regions of the brain can be modulated by attentional mechanisms during parallel cognitive processing. To investigate whether such attention-related modulations are present in the processing of pain, the regional cerebral blood flow was me...
| Publicado en: | PAIN Vol. 85; no. 1-2; pp. 19 - 31 |
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| Autores principales: | , , , , |
| Formato: | clinical trial research Journal Article |
| Publicado: |
Lippincott Williams & Wilkins
2000 Mar
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104719684&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104719684 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 03043959 22N jtl: PAIN issn: 03043959 maglogo: N pubinfo: dt: 2000 Mar vid: 85 iid: 1-2 pid: 433 pub: Lippincott Williams & Wilkins place: Baltimore, Maryland artinfo: ui: 104719684 104719684 NLM10692599 2011077354 10.1016/S0304-3959(99)00232-8 NLM10692599 104719684 ppf: 19 ppct: 12 formats: tig: atl: Pain-related cerebral activation is altered by a distracting cognitive task. aug: au: Petrovic, P Petersson, K M Ghatan, P H Stone-Elander, S Ingvar, M affil: Section of Clinical Neurophysiology, Department of Clinical Neuroscience, Karolinska Institute/Karolinska Hospital, 171 76, Stockholm, Sweden. sug: subj: Attention Cerebral Cortex Physiopathology Cognition Pain Physiopathology Pain Psychosocial Factors Adult Cerebral Cortex Radiography Cerebrovascular Circulation Physiology Cold Electroencephalography Human Male Memory, Short Term Pain Radiography Pressure Tomography, Emission-Computed Clinical Trials Adult: 19-44 years Male ab: It has previously been suggested that the activity in sensory regions of the brain can be modulated by attentional mechanisms during parallel cognitive processing. To investigate whether such attention-related modulations are present in the processing of pain, the regional cerebral blood flow was measured using [(15)O]butanol and positron emission tomography in conditions involving both pain and parallel cognitive demands. The painful stimulus consisted of the standard cold pressor test and the cognitive task was a computerised perceptual maze test. The activations during the maze test reproduced findings in previous studies of the same cognitive task. The cold pressor test evoked significant activity in the contralateral S1, and bilaterally in the somatosensory association areas (including S2), the ACC and the mid-insula. The activity in the somatosensory association areas and periaqueductal gray/midbrain were significantly modified, i.e. relatively decreased, when the subjects also were performing the maze task. The altered activity was accompanied with significantly lower ratings of pain during the cognitive task. In contrast, lateral orbitofrontal regions showed a relative increase of activity during pain combined with the maze task as compared to only pain, which suggests the possibility of the involvement of frontal cortex in modulation of regions processing pain. pubtype: Academic Journal doctype: clinical trial research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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