Changes in the pattern of infection caused by Streptococcus pyogenes.

The distribution of T- and M-protein antigens was determined in 12,469 cultures of Streptococcus pyogenes sent to a reference laboratory. Of these 7232 (58%) were isolates from hospital patients, 249 (2%) from hospital staff and 4988 (40%) from the community. The survey extended from January 1980 to...

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Publicado en:Epidemiology & Infection Vol. 100; no. 2; pp. 257 - 270
Autores principales: Gaworzewska, E, Colman, G
Formato: Journal Article
Publicado: Cambridge University Press Mar1988
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Mar1988
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      pub: Cambridge University Press
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        atl: Changes in the pattern of infection caused by Streptococcus pyogenes.
      aug:
        au:
          Gaworzewska, E
          Colman, G
        affil: Division of Hospital Infection, Central Public Health Laboratory, London.
      sug:
        subj:
          Streptococcal Infections Microbiology
          Streptococcus Classification
          Agglutination Tests
          Antigens, Bacterial Analysis
          Skin Diseases, Infectious Epidemiology
          Skin Diseases, Infectious Microbiology
          Female
          Glomerulonephritis Epidemiology
          Glomerulonephritis Etiology
          Glomerulonephritis Microbiology
          Great Britain
          Immunodiffusion
          Meat
          Occupational Diseases Epidemiology
          Occupational Diseases Microbiology
          Pregnancy
          Puerperal Infection Microbiology
          Rheumatic Fever Epidemiology
          Rheumatic Fever Microbiology
          Scarlet Fever Epidemiology
          Scarlet Fever Microbiology
          Sepsis Epidemiology
          Sepsis Microbiology
          Serotyping
          Streptococcal Infections Epidemiology
          Streptococcus Immunology
          Streptococcus
          Female
      ab: The distribution of T- and M-protein antigens was determined in 12,469 cultures of Streptococcus pyogenes sent to a reference laboratory. Of these 7232 (58%) were isolates from hospital patients, 249 (2%) from hospital staff and 4988 (40%) from the community. The survey extended from January 1980 to June 1987. During this time the numbers of isolates of M-types 6, 49 and 81 rose then fell, being replaced by types 1, 3 and 28. The proportion of isolates of M-types 4 and 12 remained constant. Few strains were received from cases of nephritis or rheumatic fever but there has been an increase in the number of strains from serious infections and deaths. Forty-four of the 55 (80%) strains received since 1985 from fatal infections have belonged to M-type 1. All other strains, bar two, received from fatal infections in those years belonged to M-type 3. Representatives of M-type 1 were also associated with erysipelas. Types 3 and 4 predominated among the isolates from scarlet fever, types 1, 4, 12 and 49 from nephritis, types 49 and 81 from skin infections in meat workers and type 28 in cases of puerperal sepsis. The M-typability rate was 97% but new M antigens await definition among strains causing pyoderma.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
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