The characterization and pathological significance of gastric Campylobacter-like organisms in the ferret: a model for chronic gastritis?
Gastric campylobacter-like organisms (CLO) were isolated from gastric tissues removed at sacrifice from 17 mature ferrets; all animals were colonized, but no macroscopic mucosal lesions or histological features of chronic gastritis were seen. The isolates resembled Campylobacter pylori in many cultu...
| Publicado en: | Epidemiology & Infection Vol. 101; no. 2; pp. 269 - 279 |
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| Autores principales: | , , , |
| Formato: | Journal Article |
| Publicado: |
Cambridge University Press
Mar1990
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104758396&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104758396 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09502688 2S0 jtl: Epidemiology & Infection issn: 09502688 maglogo: N pubinfo: dt: Mar1990 vid: 101 iid: 2 pid: 15979 pub: Cambridge University Press artinfo: ui: 104758396 104758396 NLM3181311 2011117860 10.1017/S0950268800054182 NLM3181311 PMC2249373 104758396 ppf: 269 ppct: 10 formats: tig: atl: The characterization and pathological significance of gastric Campylobacter-like organisms in the ferret: a model for chronic gastritis? aug: au: Tompkins, D S Wyatt, J I Rathbone, B J West, A P affil: Department of Microbiology, University of Leeds. sug: subj: Campylobacter Campylobacter Infections Microbiology Mammals Models, Biological Gastritis Microbiology Animals Campylobacter Classification Gastric Mucosa Microbiology Gastric Mucosa Pathology ab: Gastric campylobacter-like organisms (CLO) were isolated from gastric tissues removed at sacrifice from 17 mature ferrets; all animals were colonized, but no macroscopic mucosal lesions or histological features of chronic gastritis were seen. The isolates resembled Campylobacter pylori in many cultural and biochemical characteristics, and produced substantial urease activity, but there were sufficient differences from C. pylori to suggest that ferret gastric CLO represents a separate species. Comparison of human C. pylori and ferret gastric CLO may help to elucidate the pathogenicity of the former in patients with gastritis, and the ferret may serve as a useful animal model for the study of C. pylori infection. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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