Intra-ocular pressure changes during rapid sequence induction of anaesthesia. A comparison between thiopentone and suxamethonium and thiopentone and atracurium.
The changes in intra-ocular pressure associated with two different anaesthetic induction and tracheal intubation techniques were compared (n = 30). After pre-oxygenation, Group A received thiopentone (5 mg/kg) followed by suxamethonium (1.5 mg/kg), both within 25 seconds, and Group B atracurium (0.5...
| Publicado en: | Anaesthesia Vol. 43; no. 12; pp. 1005 - 1011 |
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| Autores principales: | , , , , |
| Formato: | clinical trial research Journal Article |
| Publicado: |
Wiley-Blackwell
Dec1988
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104758810&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104758810 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00032409 1WP jtl: Anaesthesia issn: 00032409 maglogo: Y pubinfo: dt: Dec1988 vid: 43 iid: 12 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 104758810 104758810 NLM3232776 2011118274 10.1111/j.1365-2044.1988.tb05695.x NLM3232776 104758810 ppf: 1005 ppct: 6 formats: tig: atl: Intra-ocular pressure changes during rapid sequence induction of anaesthesia. A comparison between thiopentone and suxamethonium and thiopentone and atracurium. aug: au: Edmondson, L Lindsay, S L Lanigan, L P Woods, M Chew, H E affil: Department of Anaesthesia, Whipps Cross Hospital, Leytonstone, London. sug: subj: Anesthesia, Intravenous Atracurium Pharmacodynamics Intraocular Pressure Drug Effects Succinylcholine Pharmacodynamics Thiopental Pharmacodynamics Adolescence Adult Aged Human Intubation, Intratracheal Middle Age Statistics Time Factors Clinical Trials Adolescent: 13-18 years Adult: 19-44 years Aged: 65+ years Middle Aged: 45-64 years ab: The changes in intra-ocular pressure associated with two different anaesthetic induction and tracheal intubation techniques were compared (n = 30). After pre-oxygenation, Group A received thiopentone (5 mg/kg) followed by suxamethonium (1.5 mg/kg), both within 25 seconds, and Group B atracurium (0.5 mg/kg) followed by thiopentone (5 mg/kg) again both within 25 seconds. Tracheal intubation occurred after one minute in Group A and 2 minutes in Group B to allow for full paralysis. In Group A intra-ocular pressure did not alter significantly from baseline and the maximum increase was only 0.93 mmHg. The statistical type II error risk was consistently below 55% and all 95% confidence limits included negative values. Intra-ocular pressure in Group B was consistently lower than baseline (p less than 0.05) but with a longer induction-intubation interval. These results therefore provide valuable information about the 'balance of risks' when choosing a muscle relaxant for an inadequately starved patient with a penetrating eye injury. pubtype: Academic Journal doctype: clinical trial research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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