The dominant class of somatosensory neurone recorded in the spinal dorsal horn of awake sheep has wide dynamic range properties.

In order to investigate the properties of dorsal horn neurones in the absence of the distorting influences of anaesthesia, preparative surgery, prior training or excessive restraint, recordings have been made in sheep chronically prepared for single-cell recording. Within the limitations of sampling...

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Publicado en:PAIN Vol. 61; no. 1; pp. 133 - 139
Autores principales: Herrero, J F, Headley, P M, Herrero, Juan F, Headley, Max P
Formato: research Journal Article
Publicado: Lippincott Williams & Wilkins 1995 Apr
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 1995 Apr
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      pub: Lippincott Williams & Wilkins
      place: Baltimore, Maryland
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        10.1016/0304-3959(94)00152-5
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        atl: The dominant class of somatosensory neurone recorded in the spinal dorsal horn of awake sheep has wide dynamic range properties.
      aug:
        au:
          Herrero, J F
          Headley, P M
          Herrero, Juan F
          Headley, Max P
        affil: Department of Physiology, University of Bristol, The School of Medical Sciences, Bristol BS8 1TD UK
      sug:
        subj:
          Evoked Potentials, Somatosensory Physiology
          Neurons Physiology
          Spinal Cord Physiology
          Animals
          Female
          Mechanoreceptors Physiology
          Restraint, Physical
          Sheep
          Spinal Cord
          Female
      ab: In order to investigate the properties of dorsal horn neurones in the absence of the distorting influences of anaesthesia, preparative surgery, prior training or excessive restraint, recordings have been made in sheep chronically prepared for single-cell recording. Within the limitations of sampling error of dorsal horn neurones with cutaneous receptive fields, the cell type most frequently encountered had wide dynamic range (WDR; convergent; multireceptive) properties; these accounted for 59% of the 46 neurones that were examined in detail. High-threshold mechanoreceptive (nocispecific) and low-threshold mechanoreceptive neurones formed 11% and 30% of the sample, respectively. These and other data indicate that under normal physiological conditions in the awake state, many spinal neurones do indeed have WDR properties, implying that these cells have an important function in nociceptive processing.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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