The properties of vitamin B12 deficiency in the patients of an outpatient clinic.
Objective: The aim of this study is to evaluate the properties of vitamin B12 deficiency and predisposing factors in the patients of an outpatient clinic. Material and Methods: Four hundred patients with vitamin B12 deficiency were studied. Anthropometric measures, biochemical analysis, gastric pari...
| Publicado en: | Turkiye Klinikleri Journal of Medical Sciences Vol. 30; no. 6; pp. 1845 - 1852 |
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| Autores principales: | , , , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Turkiye Klinikleri
Dec2010
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104812770&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104812770 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 13000292 1VOP jtl: Turkiye Klinikleri Journal of Medical Sciences issn: 13000292 maglogo: N pubinfo: dt: Dec2010 vid: 30 iid: 6 pid: 67298 pub: Turkiye Klinikleri artinfo: ui: 104812770 2010937909 10.5336/medsci.2009-12245 104812770 ppf: 1845 ppct: 7 formats: fmt: @attributes: type: P tig: atl: The properties of vitamin B12 deficiency in the patients of an outpatient clinic. aug: au: Erden, Sacide Sakar, Sule Koc, Zeynep Sen, Fatma Cakir, Habibe Genlincik, Asli Kiliç, Leyla Özdener, Lutfiye affil: Department of Internal Medicine Istanbul University Istanbul Faculty of Medicine sug: subj: Vitamin B12 Deficiency Epidemiology Academic Medical Centers Adolescence Adult Antibodies Body Composition Case Control Studies Chi Square Test Comorbidity Data Analysis Software Descriptive Statistics Endoscopy, Gastrointestinal Feces Analysis Goodness of Fit Chi Square Test Human Hyperlipidemia Hypertension Kruskal-Wallis Test Mann-Whitney U Test Middle Age Obesity Outpatients Thyroid Diseases Turkiye Adolescent: 13-18 years Adult: 19-44 years Middle Aged: 45-64 years ab: Objective: The aim of this study is to evaluate the properties of vitamin B12 deficiency and predisposing factors in the patients of an outpatient clinic. Material and Methods: Four hundred patients with vitamin B12 deficiency were studied. Anthropometric measures, biochemical analysis, gastric parietal cell antibodies and parasites in stool of the patients, antigliadin antibody survey and upper gastrointestinal system endoscopy were performed. Additionally, randomly selected 100 patients with low and 100 healthy subjects with normal serum vitamin B12 levels were questioned about food intake. Results: Overall ratio of vitamin B12 deficiency among outpatients was 4%. Coexisting diseases such as diabetes mellitus (12.3%), hypertension (42.0%), hyperlipidemia (42.0%) and obesity (42.0%) were determined. Nearly a quarter (22,8%) had autoimmune thyroid disease. A group of patients had other problems that may have caused malabsorption such as Helicobacter pylori gastritis (66/85= 77.6%), antigastric parietal cell antibody positivity (37/85= 43.5%), antigliadin antibody positivity (40/61= 65.6%), and others (3.3%). The patient group with vitamin B12 deficiency consumed significantly less meat (p< 0.001), chicken (p< 0.001), fish (p= 0.002), milk (p= 0.027) and eggs (p< 0.001), smaller number of meals (p= 0.013) and significantly higher amounts of fiber (p< 0.001) and vegetables (p= 0.037) when compared with the control group. Conclusion: Vitamin B12 deficiency was considered to be related mainly with improper and defective alimentation. However, malabsorption-related diseases may also contribute to vitamin B12 deficiency. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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