Cognitive profile in young adults born preterm at very low birthweight.

AIM: the aim of this study was to assess cognitive function at the age of 19 years in individuals of very low birthweight (VLBW; <= 1500g) and in term-born comparison individuals. METHOD: in this hospital-based follow-up study, 55 VLBW participants (30 males, 25 females; mean birthweight 1217g, SD 2...

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Publicado en:Developmental Medicine & Child Neurology Vol. 52; no. 12; pp. 1133 - 1139
Autores principales: Løhaugen GC, Gramstad A, Evensen KA, Martinussen M, Lindqvist S, Indredavik M, Vik T, Brubakk AM, Skranes J
Formato: research Journal Article
Publicado: Wiley-Blackwell Dec2010
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Dec2010
      vid: 52
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        104813650
        104813650
        2010926138
        10.1111/j.1469-8749.2010.03743.x
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        atl: Cognitive profile in young adults born preterm at very low birthweight.
      aug:
        au:
          Løhaugen GC
          Gramstad A
          Evensen KA
          Martinussen M
          Lindqvist S
          Indredavik M
          Vik T
          Brubakk AM
          Skranes J
        affil: Department of Paediatrics and Rehabilitation, Sørlandet Hospital, Arendal, Norway. gro.c.lohaugen@ntnu.no
      sug:
        subj:
          Child Development
          Cognition
          Infant, Very Low Birth Weight
          Childbirth, Premature Physiopathology
          Achievement
          Female
          Gestational Age
          Human
          Infant, Newborn
          Intelligence
          Prospective Studies
          Male
          Neuropsychological Tests
          Stigma
          Statistics
          Nonparametric Statistics
          Young Adult
          Infant, Newborn: birth-1 month
          Female
          Male
      ab: AIM: the aim of this study was to assess cognitive function at the age of 19 years in individuals of very low birthweight (VLBW; <= 1500g) and in term-born comparison individuals. METHOD: in this hospital-based follow-up study, 55 VLBW participants (30 males, 25 females; mean birthweight 1217g, SD 233g; mean gestational age 29.1wks, SD 2.5wks) and 81 comparison individuals (42 males, 39 females; mean birthweight 3707g, SD 433g; mean gestational age 39.7wks, SD 1.2wks) were examined with a standardized IQ test (Wechsler Adult Intelligence Scale III) to assess general cognitive ability. RESULTS: over half (53%) of the VLBW participants achieved a low IQ score (defined as >1SD below the mean in the comparison group; odds ratio 6.4 vs comparison individuals; 95% confidence interval 2.8-14.4; p<0.001). None of the VLBW group, compared with 22% of the comparison individuals, achieved a high IQ score (>1SD above the comparison mean). VLBW participants scored lower than comparison individuals on full, verbal, and performance IQ, as well as on all four indices (p <=0.001). The subtest profile indicated problems on all subtests, but especially on those related to arithmetic and visual-perceptual tasks. INTERPRETATIONS: few studies have undertaken a comprehensive assessment of general cognitive outcome (IQ) among young adults of VLBW. Our results indicate that VLBW seems to have a global and lasting impact on cognitive ability. Full-scale IQ assessment may reveal important learning problems in young adults of VLBW, and should be performed to inform appropriate assistance to enhance academic achievement and the chances of permanent employment as adults.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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