CT colonography and transient bacteraemia: implications for antibiotic prophylaxis.

Objectives: To determine the prevalence of transient bacteraemia after CT colonography (CTC).Methods: Blood cultures were obtained at 5, 10 and 15 min after CTC from 100 consecutive consenting patients. Blood samples were cultured in both aerobic and anaerobic media and positive blood culture sample...

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Publicado en:European Radiology Vol. 21; no. 2; pp. 360 - 366
Autores principales: Ridge CA, Carter MR, Browne LP, Ryan R, Hegarty C, Schaffer K, Malone DE, Ridge, C A, Carter, M R, Browne, L P, Ryan, R, Hegarty, C, Schaffer, K, Malone, D E
Formato: research Journal Article
Publicado: Springer Nature Feb2011
Acceso en línea:Ver este registro en EBSCOhost
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        atl: CT colonography and transient bacteraemia: implications for antibiotic prophylaxis.
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          Ridge CA
          Carter MR
          Browne LP
          Ryan R
          Hegarty C
          Schaffer K
          Malone DE
          Ridge, C A
          Carter, M R
          Browne, L P
          Ryan, R
          Hegarty, C
          Schaffer, K
          Malone, D E
        affil: Department of Radiology, St Vincent's University Hospital, Dublin, Ireland
      sug:
        subj:
          Antibiotics Therapeutic Use
          Bacteremia Epidemiology
          Bacteremia Prevention and Control
          Colonography, Computed Tomographic Statistics and Numerical Data
          Adult
          Aged
          Aged, 80 and Over
          Female
          Incidence
          Ireland
          Male
          Middle Age
          Risk Assessment
          Risk Factors
          Adult: 19-44 years
          Aged: 65+ years
          Aged, 80 & over
          Middle Aged: 45-64 years
          Female
          Male
      ab: Objectives: To determine the prevalence of transient bacteraemia after CT colonography (CTC).Methods: Blood cultures were obtained at 5, 10 and 15 min after CTC from 100 consecutive consenting patients. Blood samples were cultured in both aerobic and anaerobic media and positive blood culture samples were analysed by a microbiologist.Results: Blood culture samples were positive for growth in sixteen patients. All positive blood culture samples were confirmed skin contaminants. There were no cases of significant bacteraemia. The estimated significant bacteraemia rate as a result of CTC is 0-3.7%, based on 95% confidence intervals around extreme results using Wilson's score method.Conclusions: American Heart Association and National Institute for Clinical Excellence guidelines advise that antibiotic prophylaxis before lower gastrointestinal endoscopy is not indicated in patients with at risk cardiac lesions (ARCL) as the risk of a transient bacteraemia leading to infective endocarditis is low. These data show that the prevalence of transient bacteraemia after CTC is also low. It follows that patients with ARCL do not require antibiotic prophylaxis before CTC.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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