Simultaneous assessment of liver volume and whole liver fat content: a step towards one-stop shop preoperative MRI protocol.
Objective: The purpose of this study was to evaluate the ability of a whole liver volume (WLV) segmentation algorithm to measure fat fraction (FF).Methods: Twenty consecutive patients with histologically proven fatty liver disease underwent dual-echo in-phase/out-of-phase MRI and magnetic resonance...
| Publicado en: | European Radiology Vol. 21; no. 2; pp. 301 - 310 |
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| Autores principales: | , , , , , , , , , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Springer Nature
Feb2011
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104817078&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104817078 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09387994 NPH jtl: European Radiology issn: 09387994 maglogo: N pubinfo: dt: Feb2011 vid: 21 iid: 2 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 104817078 57853986 NLM20814683 2010941069 10.1007/s00330-010-1941-1 NLM20814683 104817078 ppf: 301 ppct: 9 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Simultaneous assessment of liver volume and whole liver fat content: a step towards one-stop shop preoperative MRI protocol. aug: au: d'Assignies G Kauffmann C Boulanger Y Bilodeau M Vilgrain V Soulez G Tang A d'Assignies, Gaspard Kauffmann, Claude Boulanger, Yvan Bilodeau, Marc Vilgrain, Valérie Soulez, Gilles Tang, An affil: Department of Medical Imaging, University of Montreal and Centre de recherche, Centre hospitalier de l'Université de Montréal (CRCHUM), Hôpital Saint-Luc, 1058 rue Saint-Denis, Montréal, Québec, Canada sug: subj: Adipose Tissue Pathology Algorithms Fatty Liver Pathology Image Interpretation, Computer Assisted Methods Diagnostic Imaging Methods Liver Pathology Adult Aged Fatty Liver Surgery Female Human Image Enhancement Methods Magnetic Resonance Imaging Male Middle Age Body Weights and Measures Preoperative Care Methods Reproducibility of Results Sensitivity and Specificity Adult: 19-44 years Aged: 65+ years Middle Aged: 45-64 years Female Male ab: Objective: The purpose of this study was to evaluate the ability of a whole liver volume (WLV) segmentation algorithm to measure fat fraction (FF).Methods: Twenty consecutive patients with histologically proven fatty liver disease underwent dual-echo in-phase/out-of-phase MRI and magnetic resonance spectroscopy (MRS) at 1.5 T. Two readers independently performed semiautomatic 3D liver segmentation on the out-of-phase sequences using an active contour model. FF was calculated for voxels, segments and WLV. Segmentation inter-observer reproducibility was assessed by intra-class correlation coefficient (ICC) for WLV and FF. Fat fraction correlation and agreement as determined by histology, MRS and MRI were determined.Results: ICC was 0.999 (95% CI: 0.999-1, P < 0.001) for WLV FF calculation and 0.996 (95% CI: 0.990-0.998, P < 0.001) for whole liver volume calculations. Strong correlations were found between FF measured by histology, MRS and WLV-MRI. A Bland-Altman analysis showed a good agreement between FF measured by MRS and WLV-MRI. No systematic variations of FF was found between segments when analyzed by ANOVA (F = 1.78, P = 0.096).Conclusion: This study shows that a reproducible whole liver volume segmentation method to measure fat fraction can be performed. This strategy may be integrated to a "one-stop shop" protocol in liver surgery planning. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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