CYP2C19-guided design of a proton pump inhibitor dose regimen to avoid the need for pharmacogenetic individualisation in H. pylori eradication.
Objective: It has been demonstrated that genetic variation in CYP2C19 has a significant influence upon H. pylori eradication rates. We have determined a dosage regimen of lansoprazole that will provide EMs with exposure approximately equivalent to that obtained by PMs treated with standard doses and...
| Published in: | European Journal of Clinical Pharmacology Vol. 67; no. 3; pp. 261 - 267 |
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| Main Authors: | , |
| Format: | research tables/charts Journal Article |
| Published: |
Springer Nature
Mar2011
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| Online Access: | View this record in EBSCOhost |