Health benefits of probiotics: are mixtures more effective than single strains?
Purpose: Most studies on probiotics utilise single strains, sometimes incorporated into yoghurts. There are fewer studies on efficacy of mixtures of probiotic strains. This review examines the evidence that (a) probiotic mixtures are beneficial for a range of health-related outcomes and (b) mixtures...
| Publicado en: | European Journal of Nutrition Vol. 50; no. 1; pp. 1 - 18 |
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| Autores principales: | , , |
| Formato: | research systematic review tables/charts Journal Article |
| Publicado: |
Springer Nature
Feb2011
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104826309&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104826309 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 14366207 CR0 jtl: European Journal of Nutrition issn: 14366207 maglogo: N pubinfo: dt: Feb2011 vid: 50 iid: 1 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 104826309 58041751 10.1007/s00394-010-0166-z NLM21229254 104826309 ppf: 1 ppct: 17 formats: fmt: @attributes: type: P tig: atl: Health benefits of probiotics: are mixtures more effective than single strains? aug: au: Chapman, C. Gibson, G. Rowland, I. affil: Department of Food and Nutritional Sciences, University of Reading, Whiteknights Reading RG6 6AP UK sug: subj: Probiotics Drug Combinations Health Treatment Outcomes Funding Source Human Professional Practice, Evidence-Based PubMed Alternative Therapies Irritable Bowel Syndrome Prevention and Control Digestive System Physiology Diarrhea Prevention and Control Dermatitis, Atopic Prevention and Control Immune System Physiology Respiratory Tract Infections Prevention and Control Inflammatory Bowel Diseases Prevention and Control Helicobacter Infections Prevention and Control Models, Biological Animal Studies Colitis, Ulcerative Prevention and Control Pouchitis Prevention and Control Child United Kingdom Child: 6-12 years ab: Purpose: Most studies on probiotics utilise single strains, sometimes incorporated into yoghurts. There are fewer studies on efficacy of mixtures of probiotic strains. This review examines the evidence that (a) probiotic mixtures are beneficial for a range of health-related outcomes and (b) mixtures are more or less effective than their component strains administered separately. Results: Mixtures of probiotics had beneficial effects on the end points including irritable bowel syndrome and gut function, diarrhoea, atopic disease, immune function and respiratory tract infections, gut microbiota modulation, inflammatory bowel disease and treatment of Helicobacter pylori infection. However, only 16 studies compared the effect of a mixture with that of its component strains separately, although in 12 cases (75%), the mixture was more effective. Conclusion: Probiotic mixtures appear to be effective against a wide range of end points. Based on a limited number of studies, multi-strain probiotics appear to show greater efficacy than single strains, including strains that are components of the mixtures themselves. However, whether this is due to synergistic interactions between strains or a consequence of the higher probiotic dose used in some studies is at present unclear. pubtype: Academic Journal doctype: research systematic review tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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