Comparison of negative pressure wound therapy with an ultraportable mechanically powered device vs. traditional electrically powered device for the treatment of chronic lower extremity ulcers: A multicenter randomized-controlled trial.
The purpose of this study was to compare the ultraportable mechanically powered Smart Negative Pressure (SNaP) Wound Care System to the traditional electrically powered Vacuum-Assisted Closure (VAC) Therapy System in the treatment of chronic lower extremity wounds. This 12-center randomized-controll...
| Published in: | Wound Repair & Regeneration Vol. 19; no. 2; pp. 173 - 181 |
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| Main Authors: | , , , |
| Format: | research tables/charts randomized controlled trial Journal Article |
| Published: |
Wiley-Blackwell
Mar/Apr2011
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104827807&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104827807 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 10671927 DPV jtl: Wound Repair & Regeneration issn: 10671927 maglogo: Y pubinfo: dt: Mar/Apr2011 vid: 19 iid: 2 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 104827807 58725576 10.1111/j.1524-475X.2010.00658.x NLM21362084 104827807 ppf: 173 ppct: 8 formats: fmt: @attributes: type: P tig: atl: Comparison of negative pressure wound therapy with an ultraportable mechanically powered device vs. traditional electrically powered device for the treatment of chronic lower extremity ulcers: A multicenter randomized-controlled trial. aug: au: Armstrong, David G. Marston, William A. Reyzelman, Alexander M. Kirsner, Robert S. affil: Southern Arizona Limb Salvage Alliance (SALSA), University of Arizona College of Medicine, Tuscon, Arizona sug: subj: Venous Ulcer Negative Pressure Wound Therapy Human Funding Source Randomized Controlled Trials Multicenter Studies United States T-Tests Kaplan-Meier Estimator Data Analysis Software Middle Age Aged Aged, 80 and Over Descriptive Statistics Male Female Middle Aged: 45-64 years Aged: 65+ years Aged, 80 & over Male Female ab: The purpose of this study was to compare the ultraportable mechanically powered Smart Negative Pressure (SNaP) Wound Care System to the traditional electrically powered Vacuum-Assisted Closure (VAC) Therapy System in the treatment of chronic lower extremity wounds. This 12-center randomized-controlled trial of patients with noninfected, nonischemic, nonplantar lower extremity wounds had enrolled 65 patients, as of January 5, 2010, at the time of a planned interim analysis. Subjects were randomly assigned to treatment with either the SNaP or VAC Systems. The trial evaluated treatment for up to 16 weeks or till complete closure was achieved. Fifty-three patients ( N=27 SNaP, N=26 VAC) completed at least 4 weeks of therapy. Thirty-three patients ( N=18 SNaP, N=15 VAC) completed the study with either healing or 16 weeks of therapy. At the time of planned interim analysis, no significant differences ( p=0.99) in the proportion of subjects healed between the two devices evaluated were found. In addition, the percent wound size reduction between treatment groups was not significantly different at 4, 8, 12, and 16 weeks, with noninferiority analysis at 4 weeks of treatment reaching the p-value <0.05 significance level ( p=0.019). These interim data suggest no difference in wound closure between the SNaP System and the VAC System in the population studied. We look forward to the final analysis results. pubtype: Academic Journal doctype: research tables/charts randomized controlled trial Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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