Imaging of bone marrow involvement in lymphoma: state of the art and future directions.

Accurate detection of bone marrow involvement in patients with lymphoma is of crucial importance because of the prognostic and therapeutic consequences. Bone marrow trephine biopsy (BMB) is currently regarded as the method of choice for the evaluation of the bone marrow in lymphoma, but it is invasi...

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Publicado en:Scientific World Journal Vol. 11; pp. 391 - 403
Autores principales: Kwee, Thomas, De Klerk, John, Nievelstein, Rutger, Kwee, Thomas C, de Klerk, John M H, Nievelstein, Rutger A J
Formato: research review Journal Article
Publicado: Wiley-Blackwell 2011
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Imaging of bone marrow involvement in lymphoma: state of the art and future directions.
      aug:
        au:
          Kwee, Thomas
          De Klerk, John
          Nievelstein, Rutger
          Kwee, Thomas C
          de Klerk, John M H
          Nievelstein, Rutger A J
        affil: Department of Radiology, University Medical Center Utrecht, Utrecht, The Netherlands
      sug:
        subj:
          Bone Marrow Pathology
          Lymphoma Pathology
          Bone Marrow Physiopathology
          Lymphoma Physiopathology
          Magnetic Resonance Imaging
          Tomography, Emission-Computed
      ab: Accurate detection of bone marrow involvement in patients with lymphoma is of crucial importance because of the prognostic and therapeutic consequences. Bone marrow trephine biopsy (BMB) is currently regarded as the method of choice for the evaluation of the bone marrow in lymphoma, but it is invasive, has a risk of complications, and lacks sufficient sensitivity due to the possibility of sampling errors. Bone marrow imaging, if accurate, may (partially) replace BMBand/or may improve the sensitivity of BMB by guiding the biopsy to the location that appears to be involved by lymphoma at imaging. In this scientific communication, general concepts of bone marrow imaging, state-of-the-art imaging modalities, and future imaging strategies for the assessment of the bone marrow in lymphoma will be reviewed and discussed.
      pubtype: Academic Journal
      doctype:
        research
        review
        Journal Article
      ougenre: Article
    language: English
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