Low prevalence of H. pylori infection in HIV-positive patients in the northeast of Brazil.
Background: This study conducted in Northeastern Brazil, evaluated the prevalence of H. pylori infection and the presence of gastritis in HIV-infected patients.Methods: There were included 113 HIV-positive and 141 age-matched HIV-negative patients, who underwent upper gastrointestinal endoscopy for...
| Published in: | BMC Gastroenterology Vol. 11; no. 1; pp. 13 - 14 |
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| Main Authors: | , , , , , , , , , , , , , , , , , |
| Format: | research Journal Article |
| Published: |
BioMed Central
2011
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104834398&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104834398 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 1471230X 1CHO jtl: BMC Gastroenterology issn: 1471230X maglogo: N pubinfo: dt: 2011 vid: 11 iid: 1 pid: 24147 pub: BioMed Central artinfo: ui: 104834398 104834398 NLM21333017 2010966661 10.1186/1471-230X-11-13 NLM21333017 PMC3055236 104834398 ppf: 13 ppct: 1 formats: tig: atl: Low prevalence of H. pylori infection in HIV-positive patients in the northeast of Brazil. aug: au: Fialho, Andréa Bc Braga-Neto, Manuel B Guerra, Eder Jc Fialho, André Mn Fernandes, Karine C Sun, Juliana Lm Takeda, Christianne Fv Silva, Cícero Is Queiroz, Dulciene Mm Braga, Lucia Lbc Fialho, Andréa B C Guerra, Eder J C Fialho, André M N Sun, Juliana L M Takeda, Christianne F V Silva, Cícero I S Queiroz, Dulciene M M Braga, Lucia L B C affil: Clinical Research Unity - Department of Internal Medicine - Federal University of Ceará, Fortaleza, Ceará, Brazil sug: subj: HIV Infections Epidemiology HIV Infections Ethnology Helicobacter Infections Epidemiology Helicobacter Infections Ethnology Adolescence Adult Aged Brazil Case Control Studies Comorbidity Endoscopy, Gastrointestinal Female Gastritis Diagnosis Gastritis Epidemiology Gastritis Ethnology Helicobacter Infections Diagnosis Helicobacter Pylori Human Male Middle Age Prevalence Risk Factors Gastrointestinal System Microbiology Young Adult Adolescent: 13-18 years Adult: 19-44 years Aged: 65+ years Middle Aged: 45-64 years Female Male ab: Background: This study conducted in Northeastern Brazil, evaluated the prevalence of H. pylori infection and the presence of gastritis in HIV-infected patients.Methods: There were included 113 HIV-positive and 141 age-matched HIV-negative patients, who underwent upper gastrointestinal endoscopy for dyspeptic symptoms. H. pylori status was evaluated by urease test and histology.Results: The prevalence of H. pylori infection was significantly lower (p < 0.001) in HIV-infected (37.2%) than in uninfected (75.2%) patients. There were no significant differences between H. pylori status and gender, age, HIV viral load, antiretroviral therapy and the use of antibiotics. A lower prevalence of H. pylori was observed among patients with T CD4 cell count below 200/mm3; however, it was not significant. Chronic active antral gastritis was observed in 87.6% of the HIV-infected patients and in 780.4% of the control group (p = 0.11). H. pylori infection was significantly associated with chronic active gastritis in the antrum in both groups, but it was not associated with corpus chronic active gastritis in the HIV-infected patients.Conclusion: We demonstrated that the prevalence of H. pylori was significantly lower in HIV-positive patients compared with HIV-negative ones. However, corpus gastritis was frequently observed in the HIV-positive patients, pointing to different mechanisms than H. pylori infection in the genesis of the lesion. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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