Performance of radiological methods in diagnosing hepatocellular carcinoma preoperatively in a recipient of living related liver transplantation: comparison with step section histopathology.
Purpose: The aim of the present study was to evaluate the performance of multidetector-row CT (MDCT) and magnetic resonance imaging (MRI) in diagnosing hepatocellular carcinoma (HCC) preoperatively in living related liver transplantation (LRLT) recipients with liver cirrhosis and HCC.Materials and M...
| Publicado en: | Japanese Journal of Radiology Vol. 29; no. 2; pp. 129 - 138 |
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| Autores principales: | , , , , , , , , , , , , , , , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Springer Nature
Feb2011
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104835092&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104835092 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 18671071 AUCM jtl: Japanese Journal of Radiology issn: 18671071 maglogo: N pubinfo: dt: Feb2011 vid: 29 iid: 2 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 104835092 58664508 NLM21359938 2010967472 10.1007/s11604-010-0528-8 NLM21359938 104835092 ppf: 129 ppct: 9 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Performance of radiological methods in diagnosing hepatocellular carcinoma preoperatively in a recipient of living related liver transplantation: comparison with step section histopathology. aug: au: Hirakawa M Yoshimitsu K Irie H Tajima T Nishie A Asayama Y Ishigami K Kakihara D Taketomi A Aishima S Honda H Hirakawa, Masakazu Yoshimitsu, Kengo Irie, Hiroyuki Tajima, Tsuyoshi Nishie, Akihiro Asayama, Yoshiki Ishigami, Kousei Kakihara, Daisuke Taketomi, Akinobu affil: Department of Clinical Radiology, Kyushu University Graduate School of Medical Sciences, Higashi-ku, Fukuoka, Japan sug: subj: Carcinoma, Hepatocellular Diagnosis Liver Cirrhosis Diagnosis Liver Neoplasms Diagnosis Liver Transplantation Living Donors Magnetic Resonance Imaging Methods Tomography, X-Ray Computed Methods Carcinoma, Hepatocellular Pathology Carcinoma, Hepatocellular Radiography Female Human Liver Cirrhosis Pathology Liver Cirrhosis Radiography Liver Neoplasms Pathology Liver Neoplasms Radiography Male Predictive Value of Tests Preoperative Period ROC Curve Sensitivity and Specificity Female Male ab: Purpose: The aim of the present study was to evaluate the performance of multidetector-row CT (MDCT) and magnetic resonance imaging (MRI) in diagnosing hepatocellular carcinoma (HCC) preoperatively in living related liver transplantation (LRLT) recipients with liver cirrhosis and HCC.Materials and Methods: A total of 25 LRLT recipients with 89 pathologically proved HCCs underwent dynamic 4-row MDCT (5 mm collimation) and MRI within 1 month before LRLT. The images were reviewed for the diagnosis of HCC on a tumor-by-tumor basis by three observers independently and randomly using explanted specimens as the gold standard. The diagnostic accuracy of these techniques in the detection of HCC was assessed with alternative free response receiver operating characteristic (ROC) analysis. The sensitivity and positive predictive values were evaluated.Results: The average values of the area under the ROC curve (Az) of MRI images were higher than those obtained with MDCT; however, no significant difference was observed (P > 0.05). The overall sensitivity of HCC with MRI was higher than that with MDCT, especially in the case of HCCs <20 mm.Conclusion: A better diagnostic performance regarding HCCs in LRLT recipients was achieved with MRI than with MDCT, although no significant difference was observed. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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