MR enterography versus capsule endoscopy in paediatric patients with suspected Crohn's disease.

Objective: The aim of this prospective study was to compare the diagnostic yield of MR enterography (MRE) with small-bowel capsule endoscopy (SBCE) in paediatric patients with suspected Crohn's disease (CD).Methods: Paediatric patients with suspected CD were considered eligible to be enrolled in the...

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Publicado en:European Radiology Vol. 21; no. 4; pp. 823 - 832
Autores principales: Casciani E, Masselli G, Di Nardo G, Polettini E, Bertini L, Oliva S, Floriani I, Cucchiara S, Gualdi G, Casciani, Emanuele, Masselli, Gabriele, Di Nardo, Giovanni, Polettini, Elisabetta, Bertini, Luca, Oliva, Salvatore, Floriani, Irene, Cucchiara, Salvatore, Gualdi, Gianfranco
Formato: research Journal Article
Publicado: Springer Nature Apr2011
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Apr2011
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      pub: Springer Nature
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        atl: MR enterography versus capsule endoscopy in paediatric patients with suspected Crohn's disease.
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          Casciani E
          Masselli G
          Di Nardo G
          Polettini E
          Bertini L
          Oliva S
          Floriani I
          Cucchiara S
          Gualdi G
          Casciani, Emanuele
          Masselli, Gabriele
          Di Nardo, Giovanni
          Polettini, Elisabetta
          Bertini, Luca
          Oliva, Salvatore
          Floriani, Irene
          Cucchiara, Salvatore
          Gualdi, Gianfranco
        affil: Radiology DEA, Azienda Policlinico Umberto I, La Sapienza University, Via del Policlinico, 155, 00166 Rome, Italy
      sug:
        subj:
          Colonoscopy Methods
          Crohn Disease Diagnosis
          Crohn Disease Pathology
          Endoscopy Methods
          Intestine, Small Pathology
          Magnetic Resonance Imaging Methods
          Adolescence
          Child
          Colitis, Ulcerative Pathology
          Female
          Human
          Male
          Pediatrics Methods
          Prospective Studies
          Reproducibility of Results
          Sensitivity and Specificity
          Adolescent: 13-18 years
          Child: 6-12 years
          Female
          Male
      ab: Objective: The aim of this prospective study was to compare the diagnostic yield of MR enterography (MRE) with small-bowel capsule endoscopy (SBCE) in paediatric patients with suspected Crohn's disease (CD).Methods: Paediatric patients with suspected CD were considered eligible to be enrolled in the study. All patients underwent diagnostic work-up including 1.5-T MRE, ileo-colonoscopy and oesophagogastroduodenoscopy. SBCE was not performed if MRE showed SB stricture or extra-intestinal findings consistent with symptoms.Results: Sixty consecutive paediatric patients (36 male; average age 14) were enrolled into the study. A positive diagnosis for CD was made in 19 patients, 29 had a negative result and 12 were affected by other gastro-intestinal conditions. SBCE was performed in 37 patients (61.7%); 23 patients were excluded (strictures in five, extra-intestinal findings in 11 and parents' refusal in seven cases). The accuracy, sensitivity, and specificity of MRE and SBCE were 98.3%, 100%, 97.6%, and 91.9%, 90.9%, 92.3%, respectively.Conclusion: Both MRE and SBCE are accurate methods for patients with suspected CD. MRE can be used as a primary imaging technique in suspected CD, in that it allows access to the ileal stricture, which forms a contra-indication for SBCE and provides extra-intestinal information.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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